2027 ICD-10-CM Diagnosis Code N48.22Cellulitis of corpus cavernosum and penis

ICD-10-CM Codes›N00–N99›N40-N53›N48

ICD-10-CM N48.22
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

N48.22 is a billable ICD-10-CM diagnosis code for cellulitis of corpus cavernosum and penis. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 727 through 728. Coders also document this condition as cellulitis of corpus cavernosum. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Inflammatory conditions of male genital organs.

Code Identity

ICD-10-CM Code
N48.22
Billable Status
Yes — Valid for Submission
Code Describes
Cellulitis of corpus cavernosum and penis
Short Description
Cellulitis of corpus cavernosum and penis
Same as the full description in the CMS dataset.
Parent Code
N48.2
Other inflammatory disorders of penis

Code Classification

ChapterN00–N99Diseases of the genitourinary system
SectionN40-N53Diseases of male genital organs
CategoryN48Other disorders of penis
This CodeN48.22Cellulitis of corpus cavernosum and penis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Cellulitis of corpus cavernosum
  • Cellulitis of penis
  • Cellulitis of perineum

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to N48.22: its own notes plus those printed at N48.2 and Chapter 14. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From N48.2 Other inflammatory disorders of penis applies to 3 codes
  • balanitis (N48.1)
  • balanitis xerotica obliterans (N48.0)
  • balanoposthitis (N47.6)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 14 (N00-N99) Diseases of the genitourinary system applies to 838 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From N48.2 Other inflammatory disorders of penis applies to 3 codes
  • code (B95-B97), to identify infectious agent.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name N48.22, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming N48.22: they are not reported together with it, unless the two conditions are unrelated.

  • N49 Inflammatory disorders of male genital organs, not elsewhere classified
    inflammation of penis (N48.1, N48.2-) names N48.2-, which includes this code

Excludes2 5

These codes carry an Excludes2 note naming N48.22: its condition is not part of those codes, and both may be reported when the patient has both.

  • L02 Cutaneous abscess, furuncle and carbuncle
    abscess of male genital organs (external) (N48.2, N49.-) names N48.2, which includes this code
  • L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
    abscess of male external genital organs (N48.2, N49.-) names N48.2, which includes this code
  • L03 Cellulitis and acute lymphangitis
    cellulitis of male external genital organs (N48.2, N49.-) names N48.2, which includes this code
  • L03.31 Cellulitis of trunk
    cellulitis of male external genital organs (N48.2, N49.-) names N48.2, which includes this code
  • Block R10-R19 Symptoms and signs involving the digestive system and abdomen
    symptoms referable to male genital organs (N48-N50) names N48-N50, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR GEN013
Inflammatory conditions of male genital organs
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Cellulitis

Cellulitis is an infection of the skin and deep underlying tissues. Group A strep (streptococcal) bacteria are the most common cause. The bacteria enter your body when you get an injury such as a bruise, burn, surgical cut, or wound.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert N48.22 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
607.2 Inflam dis, penis NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About N48.22Overview

What is the ICD-10 code for cellulitis of corpus cavernosum and penis?

The ICD-10-CM code for cellulitis of corpus cavernosum and penis is N48.22 (sometimes written as N4822). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is N48.22 (Other inflammatory disorders of penis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report cellulitis of corpus cavernosum and penis on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does N48.22 group to?

When cellulitis of corpus cavernosum and penis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 727, 728, with relative weights from 0.8220 to 1.3694 depending on complications. Higher weights mean higher Medicare reimbursement.

Can N48.22 be reported with N48.1?

Not as a rule. The Excludes1 note at N48.2, which applies to N48.22, lists "balanitis (N48.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

Does N48.22 need an additional code?

When the condition applies, yes. The Use Additional Code note at N48.2, which applies to N48.22, reads: code (B95-B97), to identify infectious agent.. The additional code is reported after N48.22.