MS-DRG · FY 2026 v43.0

MS-DRG 727 – Inflammation of the Male Reproductive System with MCC

A Medical DRG in MDC 12 (Diseases & Disorders of the Male Reproductive System). Inpatient cases group to DRG 727 when the ICD-10-CM principal diagnosis is one of the 67 codes listed below and a secondary diagnosis on the major complication or comorbidity (MCC) list is present. Its FY 2026 relative weight is 1.4829 with a geometric mean length of stay of 4.5 days.

Medical DRG – assigned by principal diagnosis✓ Official CMS v43.0 dataset
1.4829
Relative Weight
4.5
Geometric Mean LOS (days)
6.0
Arithmetic Mean LOS (days)
67
Principal Diagnosis Codes

Severity family

DRG 727with MCCWeight 1.4829 · GMLOS 4.5 daysDRG 728without MCCWeight 0.8112 · GMLOS 2.9 days
How a case is assigned to DRG 727

The grouper first assigns the case to MDC 12 from the principal diagnosis and finds no qualifying operating-room procedure (this is a Medical DRG; ICD-10-PCS codes do not drive assignment here), then applies the severity split from secondary diagnoses: with MCC → 727; without MCC → 728.

ICD-10-CM

Principal Diagnosis Codes 67 codes · 21 categories

67 of 67 shown
A18 Tuberculosis of other organs2 codes
  • A18.14 Tuberculosis of prostate
  • A18.15 Tuberculosis of other male genital organs
A51 Early syphilis1 code
  • A51.0 Primary genital syphilis
A54 Gonococcal infection7 codes
  • A54.00 Gonococcal infection of lower genitourinary tract, unspecified
  • A54.09 Other gonococcal infection of lower genitourinary tract
  • A54.1 Gonococcal infection of lower genitourinary tract with periurethral and accessory gland abscess
  • A54.21 Gonococcal infection of kidney and ureter
  • A54.22 Gonococcal prostatitis
  • A54.23 Gonococcal infection of other male genital organs
  • A54.29 Other gonococcal genitourinary infections
A55 Chlamydial lymphogranuloma (venereum)1 code
  • A55 Chlamydial lymphogranuloma (venereum)
A56 Other sexually transmitted chlamydial diseases5 codes
  • A56.00 Chlamydial infection of lower genitourinary tract, unspecified
  • A56.01 Chlamydial cystitis and urethritis
  • A56.09 Other chlamydial infection of lower genitourinary tract
  • A56.2 Chlamydial infection of genitourinary tract, unspecified
  • A56.8 Sexually transmitted chlamydial infection of other sites
A57 Chancroid1 code
A58 Granuloma inguinale1 code
  • A58 Granuloma inguinale
A59 Trichomoniasis4 codes
  • A59.00 Urogenital trichomoniasis, unspecified
  • A59.02 Trichomonal prostatitis
  • A59.03 Trichomonal cystitis and urethritis
  • A59.09 Other urogenital trichomoniasis
A60 Anogenital herpesviral [herpes simplex] infections6 codes
  • A60.00 Herpesviral infection of urogenital system, unspecified
  • A60.01 Herpesviral infection of penis
  • A60.02 Herpesviral infection of other male genital organs
  • A60.09 Herpesviral infection of other urogenital tract
  • A60.1 Herpesviral infection of perianal skin and rectum
  • A60.9 Anogenital herpesviral infection, unspecified
A63 Other predominantly sexually transmitted diseases, not elsewhere classified1 code
  • A63.8 Other specified predominantly sexually transmitted diseases
A64 Unspecified sexually transmitted disease1 code
  • A64 Unspecified sexually transmitted disease
B26 Mumps1 code
B37 Candidiasis3 codes
  • B37.41 Candidal cystitis and urethritis
  • B37.42 Candidal balanitis
  • B37.49 Other urogenital candidiasis
N34 Urethritis and urethral syndrome1 code
  • N34.1 Nonspecific urethritis
N41 Inflammatory diseases of prostate7 codes
  • N41.0 Acute prostatitis
  • N41.1 Chronic prostatitis
  • N41.2 Abscess of prostate
  • N41.3 Prostatocystitis
  • N41.4 Granulomatous prostatitis
  • N41.8 Other inflammatory diseases of prostate
  • N41.9 Inflammatory disease of prostate, unspecified
N43 Hydrocele and spermatocele1 code
N45 Orchitis and epididymitis4 codes
N47 Disorders of prepuce9 codes
  • N47.0 Adherent prepuce, newborn
  • N47.1 Phimosis
  • N47.2 Paraphimosis
  • N47.3 Deficient foreskin
  • N47.4 Benign cyst of prepuce
  • N47.5 Adhesions of prepuce and glans penis
  • N47.6 Balanoposthitis
  • N47.7 Other inflammatory diseases of prepuce
  • N47.8 Other disorders of prepuce
N48 Other disorders of penis4 codes
  • N48.1 Balanitis
  • N48.21 Abscess of corpus cavernosum and penis
  • N48.22 Cellulitis of corpus cavernosum and penis
  • N48.29 Other inflammatory disorders of penis
N49 Inflammatory disorders of male genital organs, not elsewhere classified6 codes
  • N49.0 Inflammatory disorders of seminal vesicle
  • N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
  • N49.2 Inflammatory disorders of scrotum
  • N49.3 Fournier gangrene
  • N49.8 Inflammatory disorders of other specified male genital organs
  • N49.9 Inflammatory disorder of unspecified male genital organ
Z41 Encounter for procedures for purposes other than remedying health state1 code
  • Z41.2 Encounter for routine and ritual male circumcision
ICD-10-PCS

Procedure Codes

Procedure codes do not drive assignment for this DRG. DRG 727 is a Medical DRG, assigned from the principal diagnosis above.

Frequently Asked Questions

What is MS-DRG 727?

MS-DRG 727 (Inflammation of the Male Reproductive System with MCC) is a medical DRG in MDC 12 (Diseases & Disorders of the Male Reproductive System). Its FY 2026 relative weight is 1.4829 with a geometric mean length of stay of 4.5 days.

What is the difference between DRG 727, 728?

All 2 share the same base category; the severity of secondary diagnoses separates them: 727 (with MCC), 728 (without MCC). A major complication or comorbidity (MCC) places the case in the highest-weighted DRG of the family; a CC in the middle; neither in the lowest.

How many diagnosis codes group to DRG 727?

67 ICD-10-CM principal diagnosis codes group to this DRG, spanning 21 three-character categories.

What is the relative weight of DRG 727?

The FY 2026 relative weight of this DRG is 1.4829, meaning reimbursement of roughly 1.48 times the average Medicare inpatient case. Multiply by a hospital's blended base rate for the approximate payment.

← PreviousDRG 726 – Benign Prostatic Hypertrophy without MCC
Source: CMS ICD-10 MS-DRG v43.0 Definitions Manual and the FY 2026 IPPS Final Rule (Table 5), effective October 1, 2025 through September 30, 2026. We publish the DRG assignments as CMS defines them and add the navigation, search, and code links.