2027 ICD-10-CM Diagnosis Code N42.31Prostatic intraepithelial neoplasia
ICD-10-CM Codes›N00–N99›N40-N53›N42
- Billable — Valid for Submission
- Chronic Condition
N42.31 is a billable ICD-10-CM diagnosis code for prostatic intraepithelial neoplasia. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 729 through 730. Coders also document this condition as low grade prostatic intraepithelial neoplasia. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified male genital disorders.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Low grade prostatic intraepithelial neoplasia
- Prostatic intraepithelial neoplasia
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to N42.31: its own notes plus those printed at Chapter 14. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- PIN
- Prostatic intraepithelial neoplasia I (PIN I)
- Prostatic intraepithelial neoplasia II (PIN II)
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- prostatic intraepithelial neoplasia III (PIN III) (D07.5)
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- certain conditions originating in the perinatal period (P04-P96)
- certain infectious and parasitic diseases (A00-B99)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name N42.31, its category, or a range that includes it.
Excludes1 2
These codes carry an Excludes1 note naming N42.31: they are not reported together with it, unless the two conditions are unrelated.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Prostatic Intraepithelial Neoplasia
a premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. the neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer.
Patient EducationClinical
Prostate Diseases
The prostate is a gland in the male reproductive system. It lies just below the bladder. It makes fluid that is part of semen.
The full article covers:
- What is the prostate?
- What are prostate diseases?
- Who is more likely to develop prostate diseases?
- What are the symptoms of prostate diseases?
- How are prostate diseases diagnosed?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert N42.31 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code History & ChangesHistory
Replacement N42.31 replaces the following previously assigned code(s):
- N42.3 - Dysplasia of prostate
Questions About N42.31Overview
What is the ICD-10 code for prostatic intraepithelial neoplasia?
The ICD-10-CM code for prostatic intraepithelial neoplasia is N42.31 (sometimes written as N4231). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is N42.31 (Dysplasia of prostate) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report prostatic intraepithelial neoplasia on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does N42.31 group to?
When prostatic intraepithelial neoplasia is the principal diagnosis on an inpatient stay, it groups to MS-DRG 729, 730, with relative weights from 0.6595 to 1.0553 depending on complications. Higher weights mean higher Medicare reimbursement.
Can N42.31 be reported with D07.5?
Not as a rule. The Excludes1 note on N42.31 lists "prostatic intraepithelial neoplasia III (PIN III) (D07.5)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What is the ICD-9 equivalent of N42.31?
Under the General Equivalence Mappings, prostatic intraepithelial neoplasia converts to ICD-9-CM 602.3 (dysplasia of prostate). The mapping is approximate, so confirm the match fits the documentation.
