2027 ICD-10-CM Diagnosis Code L81.4Other melanin hyperpigmentation
ICD-10-CM Codes›L00–L99›L80-L99›L81
- Billable — Valid for Submission
- Not Chronic
L81.4 is a billable ICD-10-CM diagnosis code for other melanin hyperpigmentation. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 606 through 607, 795. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified skin disorders.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Acquired hypermelanotic disorder
- Addison melanoderma
- Adverse effect from PUVA photochemotherapy
- Agminated lentiginosis
- Arterial dissection and lentiginosis syndrome
- Circumscribed acquired hypermelanosis
- Circumscribed hypermelanosis
- Complication of cryotherapy procedure
- Cutaneous complication of systemic sclerosis
- Deposit on gingivae
- Deposition on vulva
- Drug pigmentation
- Drug-induced hypermelanosis
- Drug-induced pigmentation
- Eruptive lentiginosis
- Familial dyskeratotic comedones
- Gastrocutaneous syndrome
- Genetic mosaic
- Genetic syndrome with hypermelanosis
- Genital lentiginosis
- Gingival pigmentation
- Hereditary diffuse melanosis
- Hereditary hypermelanosis
- Hereditary reticulate melanosis
- Hypermelanosis due to acromegaly
- Hypermelanosis due to ACTH/MSH-secreting tumor
- Hypermelanosis due to connective tissue disorder
- Hypermelanosis due to cryotherapy
- Hypermelanosis due to Cushing syndrome
- Hypermelanosis due to endocrine disorder
- Hypermelanosis due to Hodgkin's disease
- Hypermelanosis due to hormonal factor
- Hypermelanosis due to hyperthyroidism
- Hypermelanosis due to malignant ACTH/MSH-secreting tumor
- Hypermelanosis due to neoplasia
- Hypermelanosis due to nervous system disorder
- Hypermelanosis due to nutritional disorder
- Hypermelanosis due to pheochromocytoma
- Hypermelanosis following phototherapy for neonatal jaundice
- Hypermelanosis of the eyelids due to hyperthyroidism
- Hypermelanosis of undetermined etiology
- Hypermelanotic pigmentary mosaicism
- Hyperpigmentation of eyelid
- Hypotrichosis with keratosis pilaris and lentiginosis
- Keratosis pilaris
- Lentiginosis
- Lentiginosis due to PUVA
- Lentigo - freckle
- Lentigo of lip
- Lentigo simplex
- Linear and whorled nevoid hypermelanosis
- Lupus erythematosus-associated hypermelanosis
- Macule of skin
- Melanin pigmentation of oral mucosa
- Melanocytic hyperactivation
- Melanoderma
- Melanoderma cachecticorum
- Melanodermatitis toxica lichenoides
- Melanosis
- Melanosis of external genitalia
- Melanosis of mucosa of body orifice
- Melanosis of vulva
- Melanotic macule of gingival mucosa
- Melanotic macule of lip
- Melanotic macule of penis
- Metastatic malignant melanoma to skin
- Metastatic malignant melanoma with diffuse hypermelanosis
- Mucosal lentiginosis
- Nevoid lentiginosis
- Nevus spilus
- Non-specific cutaneous reaction in Hodgkin's disease
- Oral melanocytic macule
- Parasitic melanoderma
- Penile hypermelanosis
- Periorbital hypermelanosis
- Pigmentary incontinence
- Pigmentation disorder of lip
- Progressive cribriform and zosteriform hyperpigmentation
- Punctate acrokeratoderma freckle-like pigmentation
- Punctate palmoplantar keratoderma
- Riehl's melanosis
- Scleroderma-associated hypermelanosis
- Senile melanoderma
- Skin graft hyperpigmentation
- Smoker's melanosis
- Solar lentiginosis
- Solar lentigo
- Squamous cell papilloma of skin
- Universal acquired melanosis
- Vulval melanotic macule
- Vulvovaginal hypermelanosis
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to L81.4: its own notes plus those printed at L81 and Chapter 12. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Lentigo
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- nevus - see Alphabetical Index
- certain conditions originating in the perinatal period (P04-P96)
- certain infectious and parasitic diseases (A00-B99)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- lipomelanotic reticulosis (I89.8)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
- systemic connective tissue disorders (M30-M36)
- viral warts (B07.-)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name L81.4, its category, or a range that includes it.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Hyperpigmentation See Also: Pigmentation;
melanin NEC L81.4
Lentigo (congenital) L81.4
Riehl's melanosis L81.4
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Lentigo
small circumscribed melanoses resembling, but differing histologically from, freckles. the concept includes senile lentigo ('liver spots') and nevoid lentigo (nevus spilus, lentigo simplex) and may also occur in association with multiple congenital defects or congenital syndromes (e.g., peutz-jeghers syndrome).Melanosis
disorders of increased melanin pigmentation that develop without preceding inflammatory disease.
Patient EducationClinical
Skin Pigmentation Disorders
Pigmentation means coloring. Skin pigmentation disorders affect the color of your skin. Your skin gets its color from a pigment called melanin. Special cells in the skin make melanin. When these cells become damaged or unhealthy, it affects melanin production. Some pigmentation disorders affect just patches of skin.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert L81.4 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About L81.4Overview
What is the ICD-10 code for other melanin hyperpigmentation?
The ICD-10-CM code for other melanin hyperpigmentation is L81.4 (sometimes written as L814). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is L81.4 (Other disorders of pigmentation) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report other melanin hyperpigmentation on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does L81.4 group to?
When other melanin hyperpigmentation is the principal diagnosis on an inpatient stay, it groups to MS-DRG 795, 607, 606, with relative weights from 0.2022 to 1.5721 depending on complications. Higher weights mean higher Medicare reimbursement.
Can L81.4 be reported with Q82.5?
Not as a rule. The Excludes1 note at L81, which applies to L81.4, lists "birthmark NOS (Q82.5)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What is the ICD-9 equivalent of L81.4?
Under the General Equivalence Mappings, other melanin hyperpigmentation converts to ICD-9-CM 709.09 (other dyschromia). The mapping is approximate, so confirm the match fits the documentation.
