2026 ICD-10-CM Diagnosis Code K74.00Hepatic fibrosis, unspecified

ICD-10-CM Codes›K00–K95›K70-K77›K74

ICD-10-CM K74.00
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

K74.00 is a billable ICD-10-CM diagnosis code for hepatic fibrosis, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 432 through 434. The code is not accepted as a principal diagnosis by the Medicare Code Editor. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified liver disease.

Code Identity

ICD-10-CM Code
K74.00
Billable Status
Yes — Valid for Submission
Code Describes
Hepatic fibrosis, unspecified
Short Description
Hepatic fibrosis, unspecified
Same as the full description in the CMS dataset.
Parent Code
K74.0
Hepatic fibrosis

Code Classification

ChapterK00–K95Diseases of the digestive system
SectionK70-K77Diseases of liver
CategoryK74Fibrosis and cirrhosis of liver
This CodeK74.00Hepatic fibrosis, unspecified

Code EditsBilling

Medicare Code Editor checks that affect claim validity for K74.00.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Bleeding esophageal varices
  • Bleeding esophageal varices due to hepatic fibrosis
  • Boichis syndrome
  • Congenital hepatic fibrosis
  • Esophageal varices associated with another disorder
  • Fibrocystic kidney disease
  • Fibropolycystic disease of liver
  • Fibrosis of liver due to metabolic dysfunction-associated steatotic liver
  • Hepatic fibrosis
  • Hepatic schistosomiasis
  • Liver cyst
  • Neonatal diabetes, congenital hypothyroidism, congenital glaucoma, hepatic fibrosis, polycystic kidney syndrome
  • Nephronophthisis
  • Pericellular fibrosis of congenital syphilis
  • Periportal fibrosis
  • Portal fibrosis without cirrhosis
  • Septal fibrosis of liver
  • Symmer's pipe-stem fibrosis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Fibrosis, fibrotic
      • liver

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR DIG019
Other specified and unspecified liver disease
Default principal diagnosis: inpatient No · outpatient Yes

Clinical InformationClinical

  • Nephrocystin-1|Juvenile Nephronophthisis 1 Protein|NPHP1

    nephrocystin-1 (732 aa, ~83 kda) is encoded by the human nphp1 gene. this protein is involved in the modulation of signaling.

  • Nephronophthisis

    progressive tubulointerstitial injury, inherited in an autosomal recessive pattern, caused by mutations in genes involved in ciliary function, which may result in an end stage renal failure.

  • Nephronophthisis 1|Familial Juvenile Nephronophthisis|Juvenile Nephronophthisis|NPH1

    progressive tubulointerstitial nephritis inherited in an autosomal recessive manner. it is caused by mutations in the nphp1 gene. patients present with anemia, polyuria, and polydipsia during childhood. the progressive bilateral kidney damage results in renal failure.

  • NPHP1 Gene|NPHP1|NPHP1|Nephronophthisis 1 (Juvenile) Gene

    this gene is involved in the mediation of signal transduction.

  • NPHP1 wt Allele|FLJ97602|JBTS4|NPH1|Nephronophthisis 1 (Juvenile) wt Allele|SLSN1

    human nphp1 wild-type allele is located in the vicinity of 2q13 and is approximately 83 kb in length. this allele, which encodes nephrocystin-1 protein, plays a role in the progression of adhesion-dependent signaling pathways. mutations in the gene are associated with familial juvenile nephronophthisis type 1, senior-loken syndrome type 1, and joubert syndrome type 4.

  • Congenital Hepatic Fibrosis

    a congenital disorder usually inherited in an autosomal recessive pattern. it affects the hepatobiliary system and the kidneys. it is characterized by liver fibrosis, portal hypertension, and renal cysts.

Patient EducationClinical

Liver Diseases

Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement K74.00 replaces the following previously assigned code(s):

  • K74.0 - Hepatic fibrosis
FY 2021AddedAdded to the ICD-10-CM code setEffective October 1, 2020.
FY 2022–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About K74.00Overview

Is K74.00 (Hepatic fibrosis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hepatic fibrosis, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does K74.00 group to?

On inpatient claims, hepatic fibrosis, unspecified maps to MS-DRG 432, 433, 434, with relative weights from 0.7125 to 1.9682 depending on complications. Higher weights mean higher Medicare reimbursement.

Can K74.00 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because hepatic fibrosis, unspecified describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.