2027 ICD-10-CM Diagnosis Code H21.81Floppy iris syndrome
ICD-10-CM Codes›H00–H59›H15-H22›H21
- Billable — Valid for Submission
- Not Chronic
H21.81 is a billable ICD-10-CM diagnosis code for floppy iris syndrome. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 124 through 125. Coders also document this condition as bilateral intraoperative floppy iris syndrome. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified eye disorders.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Bilateral intraoperative floppy iris syndrome
- Intraoperative floppy iris syndrome
- Intraoperative floppy iris syndrome following administration of tamsulosin
- Intraoperative floppy iris syndrome of left eye
- Intraoperative floppy iris syndrome of right eye
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to H21.81: its own notes plus those printed at H21 and Chapter 7. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Intraoperative floppy iris syndrome (IFIS)
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- certain conditions originating in the perinatal period (P04-P96)
- certain infectious and parasitic diseases (A00-B99)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
- diabetes mellitus related eye conditions (E09.3-, E10.3-, E11.3-, E13.3-)
- endocrine, nutritional and metabolic diseases (E00-E88)
- injury (trauma) of eye and orbit (S05.-)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
- syphilis related eye disorders (A50.01, A50.3-, A51.43, A52.71)
Use Additional Code
Add a second code, after this one, to fully describe the condition.
Notes
General instructions on how these codes are used.
- Use an external cause code following the code for the eye condition, if applicable, to identify the cause of the eye condition
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name H21.81, its category, or a range that includes it.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Syndrome See Also: Disease;
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Eye Diseases
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Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert H21.81 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About H21.81Overview
What is the ICD-10 code for floppy iris syndrome?
The ICD-10-CM code for floppy iris syndrome is H21.81 (sometimes written as H2181). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is H21.81 (Other specified disorders of iris and ciliary body) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report floppy iris syndrome on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does H21.81 group to?
When floppy iris syndrome is the principal diagnosis on an inpatient stay, it groups to MS-DRG 125, 124, with relative weights from 0.7699 to 1.2470 depending on complications. Higher weights mean higher Medicare reimbursement.
Does H21.81 need an additional code?
When the condition applies, yes. The Use Additional Code note reads: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5). The additional code is reported after H21.81.
What is the ICD-9 equivalent of H21.81?
Under the General Equivalence Mappings, floppy iris syndrome converts to ICD-9-CM 364.81 (floppy iris syndrome). The mapping is a direct match.
