2026 ICD-10-CM Diagnosis Code D75.AGlucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia

ICD-10-CM Codes›D50–D89›D70-D77›D75

ICD-10-CM D75.A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D75.A is a billable ICD-10-CM diagnosis code for Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. Coders also document this condition as deficiency of glucose-6-phosphate dehydrogenase. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified hematologic conditions.

Code Identity

ICD-10-CM Code
D75.A
Billable Status
Yes — Valid for Submission
Code Describes
Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia
Short Description
Glucose-6-phosphate dehydrgnse (G6PD) defic without anemia
Parent Code
D75
Other and unspecified diseases of blood and blood-forming organs

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD70-D77Other disorders of blood and blood-forming organs
CategoryD75Other and unspecified diseases of blood and blood-forming organs
This CodeD75.AGlucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Deficiency of glucose-6-phosphate dehydrogenase
  • Deficiency of glucose-6-phosphate dehydrogenase with normal enzyme activity
  • Moderate deficiency of glucose-6-phosphate dehydrogenase

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

  • glucose-6-phosphate dehydrogenase G6PD deficiency with anemia D55.0

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Deficiency, deficient
      • glucose-6-phosphate dehydrogenase
        • without anemia

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD010
Other specified and unspecified hematologic conditions
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

G6PD Deficiency

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a genetic disorder that is most common in males. About 1 in 10 African American males in the United States has it. G6PD deficiency mainly affects red blood cells, which carry oxygen from the lungs to tissues throughout the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement D75.A replaces the following previously assigned code(s):

  • D55.0 - Anemia due to glucose-6-phosphate dehydrogenase deficiency
FY 2020AddedAdded to the ICD-10-CM code setEffective October 1, 2019.
FY 2021–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D75.AOverview

Is D75.A a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D75.A group to?

When Glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.