2026 ICD-10-CM Diagnosis Code D72.822Plasmacytosis

ICD-10-CM Codes›D50–D89›D70-D77›D72

ICD-10-CM D72.822
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D72.822 is a billable ICD-10-CM diagnosis code for plasmacytosis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. Coders also document this condition as non-malignant lymphocyte AND/OR plasma cell disorder. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Diseases of white blood cells.

Code Identity

ICD-10-CM Code
D72.822
Billable Status
Yes — Valid for Submission
Code Describes
Plasmacytosis
Short Description
Plasmacytosis
Same as the full description in the CMS dataset.
Parent Code
D72.82
Elevated white blood cell count

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD70-D77Other disorders of blood and blood-forming organs
CategoryD72Other disorders of white blood cells
This CodeD72.822Plasmacytosis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Non-malignant lymphocyte AND/OR plasma cell disorder
  • Plasmacytosis
  • Primary cutaneous plasmacytosis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Plasmacytosis

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD007
Diseases of white blood cells
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Plasmacytosis

    a morphologic finding indicating the presence of plasma cell infiltrates in tissues, or the presence of plasma cells in the peripheral blood.

Patient EducationClinical

Blood Disorders

Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D72.822 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
288.64 Plasmacytosis
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D72.822Overview

Is D72.822 (Elevated white blood cell count) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report plasmacytosis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D72.822 group to?

When plasmacytosis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D72.822?

Under the General Equivalence Mappings, plasmacytosis converts to ICD-9-CM 288.64 (plasmacytosis). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.