2026 ICD-10-CM Diagnosis Code D72.819Decreased white blood cell count, unspecified

ICD-10-CM CodesD50–D89D70-D77D72

ICD-10-CM D72.819
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D72.819 is a billable ICD-10-CM diagnosis code for decreased white blood cell count, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. Coders also document this condition as blood leukocyte number below reference range. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Diseases of white blood cells.

Code Identity

ICD-10-CM Code
D72.819
Billable Status
Yes — Valid for Submission
Code Describes
Decreased white blood cell count, unspecified
Short Description
Decreased white blood cell count, unspecified
Same as the full description in the CMS dataset.
Parent Code
Decreased white blood cell count

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD70-D77Other disorders of blood and blood-forming organs
CategoryD72Other disorders of white blood cells
This CodeD72.819Decreased white blood cell count, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Blood leukocyte number below reference range
  • Leukopenia

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Decreased leukocytes, unspecified
  • Leukocytopenia, unspecified
  • Leukopenia

Type 1 Excludes

  • malignant leukopenia D70.9

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Decrease(d)
      • leukocytes
    • Decrease(d)
      • white blood cell count
    • Leukocytopenia
    • Leukopenia

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD007
Diseases of white blood cells
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Leukopenia

    a decrease in the number of leukocytes in a blood sample below the normal range (leukocyte count less than 4000).

Patient EducationClinical

Blood Disorders

Your blood is living tissue made up of liquid and solids. The liquid part, called plasma, is made of water, salts and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells and platelets.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D72.819 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
288.50 Leukocytopenia NOS
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D72.819Overview

Is D72.819 (Decreased white blood cell count) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report decreased white blood cell count, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D72.819 group to?

When decreased white blood cell count, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D72.819?

Under the General Equivalence Mappings, decreased white blood cell count, unspecified converts to ICD-9-CM 288.50 (leukocytopenia NOS). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.