2026 ICD-10-CM Diagnosis Code D72.111Lymphocytic Variant Hypereosinophilic Syndrome [LHES]

ICD-10-CM Codes›D50–D89›D70-D77›D72

ICD-10-CM D72.111
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D72.111 is a billable ICD-10-CM diagnosis code for lymphocytic Variant Hypereosinophilic Syndrome [LHES]. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 814 through 816. Coders also document this condition as hypereosinophilic syndrome. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Diseases of white blood cells.

Code Identity

ICD-10-CM Code
D72.111
Billable Status
Yes — Valid for Submission
Code Describes
Lymphocytic Variant Hypereosinophilic Syndrome [LHES]
Short Description
Lymphocytic Variant Hypereosinophilic Syndrome [LHES]
Same as the full description in the CMS dataset.
Parent Code
D72.11
Hypereosinophilic syndrome [HES]

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD70-D77Other disorders of blood and blood-forming organs
CategoryD72Other disorders of white blood cells
This CodeD72.111Lymphocytic Variant Hypereosinophilic Syndrome [LHES]

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Hypereosinophilic syndrome
  • Lymphocytic hypereosinophilic syndrome

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Lymphocyte variant hypereosinophilia

Code Also

  • , if applicable, any associated lymphocytic neoplastic disorder

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Syndrome
      • hypereosinophilic (HES)
        • lymphocytic variant (LHES)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD007
Diseases of white blood cells
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hypereosinophilic Syndrome

    a heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction, including the heart, central nervous system, kidneys, lungs, gastrointestinal tract, and skin. there is a massive increase in the number of eosinophils in the blood, mimicking leukemia, and extensive eosinophilic infiltration of the various organs.

  • Eosinophils

    granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin.

Patient EducationClinical

Eosinophilic Disorders

Eosinophils are a type of white blood cell. They help fight off infections and play a role in your body's immune response. They can also build up and cause inflammation.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement D72.111 replaces the following previously assigned code(s):

  • D72.1 - Eosinophilia
FY 2021AddedAdded to the ICD-10-CM code setEffective October 1, 2020.
FY 2022–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D72.111Overview

Is D72.111 (Hypereosinophilic syndrome [HES]) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report lymphocytic Variant Hypereosinophilic Syndrome [LHES] on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D72.111 group to?

When lymphocytic Variant Hypereosinophilic Syndrome [LHES] is the principal diagnosis on an inpatient stay, it groups to MS-DRG 814, 815, 816, with relative weights from 0.6320 to 2.1267 depending on complications. Higher weights mean higher Medicare reimbursement.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.