2026 ICD-10-CM Diagnosis Code D63.1Anemia in chronic kidney disease

ICD-10-CM Codes›D50–D89›D60-D64›D63

ICD-10-CM D63.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D63.1 is a billable ICD-10-CM diagnosis code for anemia in chronic kidney disease. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 811 through 812. The code is a manifestation code that cannot be reported as the principal diagnosis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Aplastic anemia and Chronic kidney disease.

Code Identity

ICD-10-CM Code
D63.1
Billable Status
Yes — Valid for Submission
Code Describes
Anemia in chronic kidney disease
Short Description
Anemia in chronic kidney disease
Same as the full description in the CMS dataset.
Parent Code
D63
Anemia in chronic diseases classified elsewhere

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD60-D64Aplastic and other anemias and other bone marrow failure syndromes
CategoryD63Anemia in chronic diseases classified elsewhere
This CodeD63.1Anemia in chronic kidney disease

Code EditsBilling

Medicare Code Editor checks that affect claim validity for D63.1.

Manifestation diagnoses
Manifestation codes describe the manifestation of an underlying disease, not the disease itself, and therefore should not be used as a principal diagnosis.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Anemia due to chronic kidney disease stage 1
  • Anemia in chronic kidney disease
  • Anemia in chronic kidney disease stage 4
  • Anemia in chronic kidney disease stage 5
  • Anemia in end stage renal disease
  • Anemia of chronic renal failure
  • Anemia of renal disease
  • Anemia secondary to renal failure
  • Anemia, pre-end stage renal disease on erythropoietin protocol
  • Drug resistance
  • Erythropoietin resistance in anemia of chronic kidney disease

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Erythropoietin resistant anemia (EPO resistant anemia)

Code First

  • underlying chronic kidney disease CKD N18

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • due to (in) (with)
        • chronic kidney disease
    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • due to (in) (with)
        • end stage renal disease
    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • erythropoietin-resistant anemia (EPO resistant anemia)
    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • in (due to) (with)
        • chronic kidney disease
    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • in (due to) (with)
        • end stage renal disease
    • Anemia(essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
      • in (due to) (with)
        • failure, kidney (renal)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD003
Aplastic anemia
Default principal diagnosis: inpatient No · outpatient No
CCSR GEN003
Chronic kidney disease
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Drug Resistance

    diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. it should be differentiated from drug tolerance which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.

  • Drug Resistance, Bacterial

    the ability of bacteria to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. this resistance may be acquired through gene mutation or foreign dna in transmissible plasmids (r factors).

  • Drug Resistance, Fungal

    the ability of fungi to resist or to become tolerant to chemotherapeutic agents, antifungal agents, or antibiotics. this resistance may be acquired through gene mutation.

  • Drug Resistance, Microbial

    the ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. this resistance may be acquired through gene mutation or foreign dna in transmissible plasmids (r factors).

  • Drug Resistance, Multiple

    simultaneous resistance to several structurally and functionally distinct drugs.

  • Drug Resistance, Multiple, Bacterial

    the ability of bacteria to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. this resistance may be acquired through gene mutation or foreign dna in transmissible plasmids (r factors).

  • Drug Resistance, Multiple, Fungal

    the ability of fungi to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. this resistance phenotype may be attributed to multiple gene mutations.

  • Drug Resistance, Multiple, Viral

    the ability of viruses to resist or to become tolerant to several structurally and functionally distinct drugs simultaneously. this resistance phenotype may be attributed to multiple gene mutation.

  • Drug Resistance, Neoplasm

    resistance or diminished response of a neoplasm to an antineoplastic agent in humans, animals, or cell or tissue cultures.

  • Drug Resistance, Viral

    the ability of viruses to resist or to become tolerant to chemotherapeutic agents or antiviral agents. this resistance is acquired through gene mutation.

  • Drug Tolerance

    progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. it should be differentiated from drug resistance wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. it should also be differentiated from maximum tolerated dose and no-observed-adverse-effect level.

Patient EducationClinical

Anemia

If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D63.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
285.21 Anemia in chr kidney dis
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D63.1Overview

Is D63.1 (Anemia in chronic diseases classified elsewhere) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report anemia in chronic kidney disease on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D63.1 group to?

On inpatient claims, anemia in chronic kidney disease maps to MS-DRG 811, 812, with relative weights from 0.9182 to 1.4043 depending on complications. Higher weights mean higher Medicare reimbursement.

Can D63.1 be a principal diagnosis?

No. This is a manifestation code: anemia in chronic kidney disease describes the manifestation of an underlying disease rather than the disease itself, so the underlying condition is sequenced first.

What is the ICD-9 equivalent of D63.1?

Under the General Equivalence Mappings, anemia in chronic kidney disease converts to ICD-9-CM 285.21 (anemia in chr kidney dis). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.