2026 ICD-10-CM Diagnosis Code D58.1Hereditary elliptocytosis

ICD-10-CM Codes›D50–D89›D55-D59›D58

ICD-10-CM D58.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D58.1 is a billable ICD-10-CM diagnosis code for hereditary elliptocytosis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 811 through 812. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hemolytic anemia.

Code Identity

ICD-10-CM Code
D58.1
Billable Status
Yes — Valid for Submission
Code Describes
Hereditary elliptocytosis
Short Description
Hereditary elliptocytosis
Same as the full description in the CMS dataset.
Parent Code
D58
Other hereditary hemolytic anemias

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD55-D59Hemolytic anemias
CategoryD58Other hereditary hemolytic anemias
This CodeD58.1Hereditary elliptocytosis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Alport syndrome, intellectual disability, midface hypoplasia, elliptocytosis syndrome
  • Congenital nephritis
  • Elliptocytosis
  • Hereditary elliptocytosis
  • Hereditary elliptocytosis due to abnormal protein 4.1
  • Hereditary elliptocytosis due to alpha spectrin defect
  • Hereditary elliptocytosis due to beta spectrin defect in self-association
  • Hereditary elliptocytosis due to beta spectrin-ankyrin interaction
  • Hereditary elliptocytosis due to deficiency of protein 4.1
  • Hereditary elliptocytosis due to glycophorin C deficiency
  • Hereditary elliptocytosis with transient poikilocytosis
  • Homozygous hereditary elliptocytosis
  • Southeast Asian ovalocytosis
  • Stomatocytosis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Elliptocytosis (congenital)
  • Ovalocytosis (congenital) (hereditary)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disease, diseased
      • hemoglobin or Hb
        • C (Hb-C)
          • elliptocytosis
    • Disease, diseased
      • hemoglobin or Hb
        • elliptocytosis
    • Dresbach's syndrome(elliptocytosis)
    • Elliptocytosis(congenital) (hereditary)
    • Elliptocytosis(congenital) (hereditary)
      • Hb C (disease)
    • Elliptocytosis(congenital) (hereditary)
      • hemoglobin disease
    • Syndrome
      • Dresbach's (elliptocytosis)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD002
Hemolytic anemia
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Elliptocytosis

    a peripheral blood finding in which a large number of erythrocytes are shaped in an elliptical form.

  • Hereditary Elliptocytosis|Hereditary Ovalocytosis

    an inherited blood disorder in which a large number of red blood cells have an elliptical morphology.

  • SPTA1 wt Allele|Alpha-I Spectrin Gene|EL2|Elliptocytosis 2 Gene|HPP|HS3|SPH3|SPTA|Spectrin Alpha Chain, Erythrocyte Gene|Spectrin Alpha, Erythrocytic 1 wt Allele|Spectrin, Alpha, Erythrocytic 1 (Elliptocytosis 2) Gene|Spectrin, Alpha, Erythrocytic 1 Gene

    human spta1 wild-type allele is located in the vicinity of 1q23.1 and is approximately 76 kb in length. this allele, which encodes spectrin alpha chain, erythrocytic 1 protein, plays a role in erythrocyte membrane morphology. mutations in the gene are associated with elliptocytosis-2, hereditary pyropoikilocytosis and type 3 spherocytosis.

  • Stomatocytosis

    a condition where red blood cells have a central slit-like appearance.

Patient EducationClinical

Anemia

If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D58.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
282.1 Heredit elliptocytosis
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D58.1Overview

Is D58.1 (Other hereditary hemolytic anemias) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hereditary elliptocytosis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D58.1 group to?

When hereditary elliptocytosis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 811, 812, with relative weights from 0.9182 to 1.4043 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D58.1?

Under the General Equivalence Mappings, hereditary elliptocytosis converts to ICD-9-CM 282.1 (heredit elliptocytosis). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.