2026 ICD-10-CM Diagnosis Code D46.BRefractory cytopenia with multilineage dysplasia and ring sideroblasts
ICD-10-CM Codes›C00–D49›D37-D48›D46
- Billable — Valid for Submission
- Not Chronic
D46.B is a billable ICD-10-CM diagnosis code for refractory cytopenia with multilineage dysplasia and ring sideroblasts. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 811 through 812. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Myelodysplastic syndrome (MDS).
Code Identity
Code Classification
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- RCMD RS
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- with multilineage dysplasia - D46.A
- and ring sideroblasts (RCMD RS) - D46.B
- Syndrome - See Also: Disease;
- myelodysplastic - D46.9
- with
- multilineage dysplasia - D46.A
- with ringed sideroblasts - D46.B
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Cytopenia
- refractory
- with multilineage dysplasia
- and ring sideroblasts (RCMD RS)
- Syndrome
- myelodysplastic
- with
- multilineage dysplasia
- with ringed sideroblasts
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Myelodysplastic Syndromes
clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. they predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into acute myeloid leukemia.
Patient EducationClinical
Myelodysplastic Syndromes
Your bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature cells, called stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert D46.B to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About D46.BOverview
Is D46.B (Myelodysplastic syndromes) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report refractory cytopenia with multilineage dysplasia and ring sideroblasts on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does D46.B group to?
When refractory cytopenia with multilineage dysplasia and ring sideroblasts is the principal diagnosis on an inpatient stay, it groups to MS-DRG 811, 812, with relative weights from 0.9182 to 1.4043 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of D46.B?
Under the General Equivalence Mappings, refractory cytopenia with multilineage dysplasia and ring sideroblasts converts to ICD-9-CM 238.72 (low grde myelody syn les). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
