2026 ICD-10-CM Diagnosis Code D07.0Carcinoma in situ of endometrium
ICD-10-CM Codes›C00–D49›D00-D09›D07
- Billable — Valid for Submission
- Chronic Condition
D07.0 is a billable ICD-10-CM diagnosis code for carcinoma in situ of endometrium. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 736 through 741, 754 through 756. Coders also document this condition as carcinoma in situ of body of uterus. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Female reproductive system cancers - endometrium.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Carcinoma in situ of body of uterus
- Carcinoma in situ of endometrium
- Carcinoma in situ of isthmus of uterus
- Carcinoma in situ of myometrium
- Carcinoma in situ of placenta
- Carcinoma in situ of uterus
- Neoplasm of isthmus of uterus
- Neoplasm of placenta
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Myometrium
the smooth muscle coat of the uterus, which forms the main mass of the organ.Abruptio Placentae
premature separation of the normally implanted placenta from the uterus. signs of varying degree of severity include uterine bleeding, uterine muscle hypertonia, and fetal distress or fetal death.Annexin A3
a protein of the annexin family that catalyzes the conversion of 1-d-inositol 1,2-cyclic phosphate and water to 1-d-myo-inositol 1-phosphate.Annexin A4
protein of the annexin family originally isolated from the electric organ of the electric ray torpedo marmorata. it has been found in a wide range of mammalian tissue where it is localized to the apical membrane of polarized epithelial cells.Annexin A5
a protein of the annexin family isolated from human placenta and other tissues. it inhibits cytosolic phospholipase a2, and displays anticoagulant activity.Cadherins
calcium-dependent cell adhesion proteins. they are important in the formation of adherens junctions between cells. cadherins are classified by their distinct immunological and tissue specificities, either by letters (e- for epithelial, n- for neural, and p- for placental cadherins) or by numbers (cadherin-12 or n-cadherin 2 for brain-cadherin). cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.Chorionic Villi
threadlike vascular projections of the chorion. chorionic villi may be free or embedded within the decidua forming the site for exchange of substances between fetal and maternal blood (placenta).Cord Blood Stem Cell Transplantation
transplantation of stem cells collected from the fetal blood remaining in the umbilical cord and the placenta after delivery. included are the hematopoietic stem cells.Eutheria
mammals which nourish their young in utero by means of a complex placenta, and give birth to their young alive. they include primates; carnivora, whales; ruminants; bats; and rodents.Folate Receptor 2
a subtype of gpi-anchored folate receptors that is expressed in placenta and hematopoietic cells.Ichthyosis, X-Linked
chronic form of ichthyosis that is inherited as a sex-linked recessive trait carried on the x-chromosome and transmitted to the male offspring. it is characterized by severe scaling, especially on the extremities, and is associated with steroid sulfatase deficiency.Perilipin-3
a perilipin that localizes to lipid droplets; cytoplasm; endosomes; and plasma membrane, especially in macrophages. it functions as a transporter of free fatty acids to lipid droplets to promote their biogenesis and growth. it is also required for the transport of the mannose-6-phosphate receptor from endosomes to the trans-golgi network. its structure consists of four helix bundles that interact with the hydrophobic lipid droplet surface.Placenta
a highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. it includes a fetal portion (chorionic villi) derived from trophoblasts and a maternal portion (decidua) derived from the uterine endometrium. the placenta produces an array of steroid, protein and peptide hormones (placental hormones).Placenta Accreta
abnormal placentation in which all or parts of the placenta are attached directly to the myometrium due to a complete or partial absence of decidua. it is associated with postpartum hemorrhage because of the failure of placental separation.Placenta Diseases
pathological processes or abnormal functions of the placenta.Placenta Growth Factor
an angiogenic protein belonging to the vascular endothelial growth factor family of growth factors originally isolated and cloned from human placental cdna library. there are four isoforms of plgf 1-4 which result from alternative splicing. placenta growth factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.Placenta Previa
abnormal placentation in which the placenta implants in the lower segment of the uterus (the zone of dilation) and may cover part or all of the opening of the cervix. it is often associated with serious antepartum bleeding and premature labor.Placenta, Retained
a placenta that fails to be expelled after birth of the fetus. a placenta is retained when the uterus fails to contract after the delivery of its content, or when the placenta is abnormally attached to the myometrium.Placental Circulation
the circulation of blood, of both the mother and the fetus, through the placenta.Placental Extracts
extracts prepared from placental tissue; they may contain specific but uncharacterized factors or proteins with specific activities.Placental Function Tests
methods used for the assessment of placental function.Placental Hormones
hormones produced by the placenta include chorionic gonadotropin, and placental lactogen as well as steroids (estrogens; progesterone), and neuropeptide hormones similar to those found in the hypothalamus (hypothalamic hormones).Placental Insufficiency
failure of the placenta to deliver an adequate supply of nutrients and oxygen to the fetus.Placental Lactogen
a polypeptide hormone of approximately 25 kda that is produced by the syncytiotrophoblasts of the placenta, also known as chorionic somatomammotropin. it has both growth hormone and prolactin activities on growth, lactation, and luteal steroid production. in women, placental lactogen secretion begins soon after implantation and increases to 1 g or more a day in late pregnancy. placental lactogen is also an insulin antagonist.Placentation
the development of the placenta, a highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products between mother and fetus. the process begins at fertilization, through the development of cytotrophoblasts and syncytiotrophoblasts, the formation of chorionic villi, to the progressive increase in blood vessels to support the growing fetus.Plasminogen Inactivators
important modulators of the activity of plasminogen activators. the inhibitors belong to the serpin family of proteins and inhibit both the tissue-type and urokinase-type plasminogen activators.Pregnancy Proteins
proteins produced by organs of the mother or the placenta during pregnancy. these proteins may be pregnancy-specific (present only during pregnancy) or pregnancy-associated (present during pregnancy or under other conditions such as hormone therapy or certain malignancies.)Pregnancy Trimester, First
the beginning third of a human pregnancy, from the first day of the last normal menstrual period (menstruation) through the completion of 14 weeks (98 days) of gestation.S100 Calcium-Binding Protein A4
an s100 protein characterized by four helix bundles that form n- and c-terminal ef hand motifs. it functions as a homodimer and interacts with both intracellular and extracellular signaling proteins. aberrant s100a4 activity is associated with neoplasm metastasis; fibrosis; and rheumatoid arthritis.Trophoblastic Tumor, Placental Site
an uncommon variant of choriocarcinoma. it is composed almost entirely of mononuclear cytotrophoblasts (trophoblasts). because its secretion of hcg (chorionic gonadotropin) is low, a large tumor may develop before the hcg can be detected.Umbilical Cord Clamping
method of placing clamps on the umbilical cord before cutting after birth.
Table of NeoplasmsClinical
Anatomical sites in the Table of Neoplasms that reference this code family.
| Site | Malig. Primary | Malig. Secondary | Ca in situ | Benign | Uncertain | Unspec. |
|---|---|---|---|---|---|---|
| corpus › uteri | C54.9 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
| corpus › uteri › isthmus | C54.0 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
| endometrium (gland) (stroma) | C54.1 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
| fetal membrane | C58 | C79.82 | D07.0 | D26.7 | D39.2 | D49.59 |
| fundus › uterus | C54.3 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
| isthmus uteri | C54.0 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
| myometrium | C54.2 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
| placenta | C58 | C79.82 | D07.0 | D26.7 | D39.2 | D49.59 |
| stroma, endometrial | C54.1 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
| uterus, uteri, uterine | C55 | C79.82 | D07.0 | D26.9 | D39.0 | D49.59 |
| uterus, uteri, uterine › body | C54.9 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
| uterus, uteri, uterine › cornu | C54.9 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
| uterus, uteri, uterine › corpus | C54.9 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
| uterus, uteri, uterine › endometrium | C54.1 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
| uterus, uteri, uterine › fundus | C54.3 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
| uterus, uteri, uterine › isthmus | C54.0 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
| uterus, uteri, uterine › lower segment | C54.0 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
| uterus, uteri, uterine › myometrium | C54.2 | C79.82 | D07.0 | D26.1 | D39.0 | D49.59 |
Patient EducationClinical
Uterine Cancer
Uterine cancer is a cancer that forms in tissues of the uterus, which is sometimes called the womb. The uterus is the place where a fetus grows during pregnancy.
The full article covers:
- What is uterine cancer?
- Who is more likely to develop uterine cancer?
- What are the symptoms of uterine cancer?
- How is uterine cancer diagnosed?
- What are the treatments for uterine cancer?
- Can uterine cancer be prevented?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert D07.0 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About D07.0Overview
Is D07.0 (Carcinoma in situ of other and unspecified genital organs) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report carcinoma in situ of endometrium on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does D07.0 group to?
When carcinoma in situ of endometrium is the principal diagnosis on an inpatient stay, it groups to MS-DRG 736, 737, 738, 739, 740, 741, 754, 755, 756, with relative weights from 0.9605 to 3.5745 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of D07.0?
Under the General Equivalence Mappings, carcinoma in situ of endometrium converts to ICD-9-CM 233.2 (ca in situ uterus NEC). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.
