2026 ICD-10-CM Diagnosis Code C79.40Secondary malignant neoplasm of unspecified part of nervous system

AHRQ’s CCSR groups this code into broader clinical categories.

• AIDS Arteritis, Central Nervous System

  inflammation of arteries in the central nervous system that occurs in patients with acquired immunodeficiency syndrome or aids-related opportunistic infections.

• Brain Diseases

  pathologic conditions affecting the brain, which is composed of the intracranial components of the central nervous system. this includes (but is not limited to) the cerebral cortex; intracranial white matter; basal ganglia; thalamus; hypothalamus; brain stem; and cerebellum.

• Brain Diseases, Metabolic

  acquired or inborn metabolic diseases that produce brain dysfunction or damage. these include primary (i.e., disorders intrinsic to the brain) and secondary (i.e., extracranial) metabolic conditions that adversely affect cerebral function.

• Brain Diseases, Metabolic, Inborn

  brain disorders resulting from inborn metabolic errors, primarily from enzymatic defects which lead to substrate accumulation, product reduction, or increase in toxic metabolites through alternate pathways. the majority of these conditions are familial, however spontaneous mutation may also occur in utero.

• Central Nervous System

  the main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges.

• Central Nervous System Agents

  a class of drugs producing both physiological and psychological effects through a variety of mechanisms. they can be divided into specific agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and nonspecific agents, those producing effects on different target cells and acting by diverse molecular mechanisms. those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. those with specific mechanisms are classed by locus of action or specific therapeutic use. (from gilman ag, et al., goodman and gilman's the pharmacological basis of therapeutics, 8th ed, p252)

• Central Nervous System Bacterial Infections

  bacterial infections of the brain, spinal cord, and meninges, including infections involving the perimeningeal spaces.

• Central Nervous System Cysts

  congenital or acquired cysts of the brain, spinal cord, or meninges which may remain stable in size or undergo progressive enlargement.

• Central Nervous System Depressants

  a very loosely defined group of drugs that tend to reduce the activity of the central nervous system. the major groups included here are ethyl alcohol, anesthetics, hypnotics and sedatives, narcotics, and tranquilizing agents (antipsychotics and antianxiety agents).

• Central Nervous System Diseases

  diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.

• Central Nervous System Fungal Infections

  mycoses of the brain, spinal cord, and meninges which may result in encephalitis; meningitis, fungal; myelitis; brain abscess; and epidural abscess. certain types of fungi may produce disease in immunologically normal hosts, while others are classified as opportunistic pathogens, causing illness primarily in immunocompromised individuals (e.g., acquired immunodeficiency syndrome).

• Central Nervous System Helminthiasis

  infections of the brain; spinal cord; or meninges caused by helminths (parasitic worms).

• Central Nervous System Infections

  pathogenic infections of the brain, spinal cord, and meninges. dna virus infections; rna virus infections; bacterial infections; mycoplasma infections; spirochaetales infections; fungal infections; protozoan infections; helminthiasis; and prion diseases may involve the central nervous system as a primary or secondary process.

• Central Nervous System Neoplasms

  benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.

• Central Nervous System Parasitic Infections

  infections of the brain, spinal cord, and meninges caused by parasites.

• Central Nervous System Protozoal Infections

  infections of the brain, spinal cord, or meninges by single celled organisms of the former subkingdom known as protozoa. the central nervous system may be the primary or secondary site of protozoal infection. these diseases may occur as opportunistic infections or arise in immunocompetent hosts.

• Central Nervous System Sensitization

  an increased response to stimulation that is mediated by amplification of signaling in the central nervous system (cns).

• Central Nervous System Stimulants

  a loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. they work by a variety of mechanisms, but usually not by direct excitation of neurons. the many drugs that have such actions as side effects to their main therapeutic use are not included here.

• Central Nervous System Vascular Malformations

  congenital, inherited, or acquired abnormalities involving arteries; veins; or venous sinuses in the brain; spinal cord; and meninges.

• Central Nervous System Venous Angioma

  a vascular anomaly characterized by a radial or wedge-shaped arrangement of dilated veins draining into a larger vein in the brain, spinal cord, or the meninges. veins in a venous angioma are surrounded by normal nervous tissue, unlike a central nervous system cavernous hemangioma that lacks intervening nervous tissue. drainage of venous angioma is fully integrated with the body's venous system, therefore, in most cases there is no clinical signs and rare bleeding.

• Central Nervous System Viral Diseases

  viral infections of the brain, spinal cord, meninges, or perimeningeal spaces.

• Cerebral Phaeohyphomycosis

  cns infections caused by neurotropic dematiaceous fungi that contain melanin in their cell walls. the infections often result in brain abscess; encephalitis; and meningitis in patients who are often immunocompetent. the common causative fungi include members cladophialophora bantiana, exophiala dermatitidis, rhinocladiella mackenziei, and ochroconis gallopavum. r. mackenziei infection is seen almost exclusively in patients from the middle east.

• Coccidioidal Meningitis

  meningitis caused by a fungus of the genus coccidioides, endemic to the southwestern united states, south-central washington state, and parts of mexico and central and south america.

• Hemangioma, Cavernous, Central Nervous System

  a vascular anomaly composed of a collection of large, thin walled tortuous veins that can occur in any part of the central nervous system but lack intervening nervous tissue. familial occurrence is common and has been associated with a number of genes mapped to 7q, 7p and 3q. clinical features include seizures; headache; stroke; and progressive neurological deficit.

• Hereditary Central Nervous System Demyelinating Diseases

  inherited conditions characterized by a loss of myelin in the central nervous system.

• Lupus Vasculitis, Central Nervous System

  central nervous system vasculitis that is associated with systemic lupus erythematosus. clinical manifestations may include dementia; seizures; cranial nerve diseases; hemiparesis; blindness; dysphasia; and other neurological disorders.

• Lyme Neuroborreliosis

  nervous system infections caused by tick-borne spirochetes of the borrelia burgdorferi group. the disease may affect elements of the central or peripheral nervous system in isolation or in combination. common clinical manifestations include a lymphocytic meningitis, cranial neuropathy (most often a facial neuropathy), polyradiculopathy, and a mild loss of memory and other cognitive functions. less often more extensive inflammation involving the central nervous system (encephalomyelitis) may occur. in the peripheral nervous system, b. burgdorferi infection is associated with mononeuritis multiplex and polyradiculoneuritis. (from j neurol sci 1998 jan 8;153(2):182-91)

• Neurocysticercosis

  infection of the brain, spinal cord, or perimeningeal structures with the larval forms of the genus taenia (primarily t. solium in humans). lesions formed by the organism are referred to as cysticerci. the infection may be subacute or chronic, and the severity of symptoms depends on the severity of the host immune response and the location and number of lesions. seizures represent the most common clinical manifestation although focal neurologic deficits may occur. (from joynt, clinical neurology, 1998, ch27, pp46-50)

• Neuroschistosomiasis

  schistosomiasis of the brain, spinal cord, or meninges caused by infections with trematodes of the genus schistosoma (primarily schistosoma japonicum; schistosoma mansoni; and schistosoma haematobium in humans). s. japonicum infections of the nervous system may cause an acute meningoencephalitis or a chronic encephalopathy. s. mansoni and s. haematobium nervous system infections are associated with acute transverse myelitis involving the lower portions of the spinal cord. (from joynt, clinical neurology, 1998, ch27, pp61-2)

• Neurosyphilis

  infections of the central nervous system caused by treponema pallidum which present with a variety of clinical syndromes. the initial phase of infection usually causes a mild or asymptomatic meningeal reaction. the meningovascular form may present acutely as brain infarction. the infection may also remain subclinical for several years. late syndromes include general paresis; tabes dorsalis; meningeal syphilis; syphilitic optic atrophy; and spinal syphilis. general paresis is characterized by progressive dementia; dysarthria; tremor; myoclonus; seizures; and argyll-robertson pupils. (adams et al., principles of neurology, 6th ed, pp722-8)

• Toxoplasmosis, Cerebral

  infections of the brain caused by the protozoan toxoplasma gondii that primarily arise in individuals with immunologic deficiency syndromes (see also aids-related opportunistic infections). the infection may involve the brain diffusely or form discrete abscesses. clinical manifestations include seizures, altered mentation, headache, focal neurologic deficits, and intracranial hypertension. (from joynt, clinical neurology, 1998, ch27, pp41-3)

• Tuberculosis, Central Nervous System

  tuberculosis of the brain, spinal cord, or meninges (tuberculosis, meningeal), most often caused by mycobacterium tuberculosis and rarely by mycobacterium bovis. the infection may be limited to the nervous system or coexist in other organs (e.g., tuberculosis, pulmonary). the organism tends to seed the meninges causing a diffuse meningitis and leads to the formation of tuberculoma, which may occur within the brain, spinal cord, or perimeningeal spaces. tuberculous involvement of the vertebral column (tuberculosis, spinal) may result in nerve root or spinal cord compression. (from adams et al., principles of neurology, 6th ed, pp717-20)

• Vasculitis, Central Nervous System

  inflammation of blood vessels within the central nervous system. primary vasculitis is usually caused by autoimmune or idiopathic factors, while secondary vasculitis is caused by existing disease process. clinical manifestations are highly variable but include headache; seizures; behavioral alterations; intracranial hemorrhages; transient ischemic attack; and brain infarction. (from adams et al., principles of neurology, 6th ed, pp856-61)

• Vertigo

  an illusion of movement, either of the external world revolving around the individual or of the individual revolving in space. vertigo may be associated with disorders of the inner ear (ear, inner); vestibular nerve; brainstem; or cerebral cortex. lesions in the temporal lobe and parietal lobe may be associated with focal seizures that may feature vertigo as an ictal manifestation. (from adams et al., principles of neurology, 6th ed, pp300-1)

• Pia Mater

  the innermost layer of the three meninges covering the brain and spinal cord. it is the fine vascular membrane that lies under the arachnoid and the dura mater.

• Metastatic Neuroblastoma

  a neuroblastoma that has metastasized from its original site of growth to another anatomic site.

Anatomical sites in the Table of Neoplasms that reference this code family.

Cancer

Cancer is not just one disease but many diseases. Cancer begins in your cells, which are the building blocks of your body. Usually, your body forms new cells as needed, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should.

The full article covers:

• What is cancer?
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• How does cancer develop?
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• How is cancer diagnosed?
• What are the treatments for cancer?
• Can cancer be prevented?

Read the full article at MedlinePlus

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