2027 ICD-10-CM Diagnosis Code B58.89Toxoplasmosis with other organ involvement

ICD-10-CM Codes›A00–B99›B50-B64›B58

ICD-10-CM B58.89
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

B58.89 is a billable ICD-10-CM diagnosis code for toxoplasmosis with other organ involvement. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 791, 793, 867 through 869, 974 through 976. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 9 closely related codes. Coders also document this condition as acquired disseminated toxoplasmosis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Parasitic, other specified and unspecified infections.

Code Identity

ICD-10-CM Code
B58.89
Billable Status
Yes — Valid for Submission
Code Describes
Toxoplasmosis with other organ involvement
Short Description
Toxoplasmosis with other organ involvement
Same as the full description in the CMS dataset.
Parent Code
Toxoplasmosis with other organ involvement

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionB50-B64Protozoal diseases
CategoryB58Toxoplasmosis
This CodeB58.89Toxoplasmosis with other organ involvement

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acquired disseminated toxoplasmosis
  • Acute lymphadenopathic toxoplasmosis
  • Cutaneous toxoplasmosis
  • Lymphadenitis caused by Toxoplasma gondii
  • Multisystemic disseminated toxoplasmosis
  • Myelitis caused by Toxoplasma gondii
  • Parasitic infection causing myelitis
  • Protozoal myelitis

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to B58.89: its own notes plus those printed at B58, block B50-B64, and Chapter 1. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From B58 Toxoplasmosis applies to 11 codes
  • infection due to Toxoplasma gondii
From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • diseases generally recognized as communicable or transmissible

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From B58 Toxoplasmosis applies to 11 codes
  • congenital toxoplasmosis (P37.1)
From Block B50-B64 Protozoal diseases applies to 57 codes
  • amebiasis (A06.-)
  • other protozoal intestinal diseases (A07.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • carrier or suspected carrier of infectious disease (Z22.-)
  • certain localized infections - see body system-related chapters
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)
  • influenza and other acute respiratory infections (J00-J22)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • code to identify resistance to antimicrobial drugs (Z16.-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name B58.89, its category, or a range that includes it.

Applicable To 1

These notes mention B58.89.

  • O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium
    Conditions in B50-B64 names B50-B64, which includes this code

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INF009
Parasitic, other specified and unspecified infections
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Toxoplasmosis

    the acquired form of infection by toxoplasma gondii in animals and man.

Patient EducationClinical

Toxoplasmosis

Toxoplasmosis is a disease caused by the parasite Toxoplasma gondii. More than 60 million people in the U.S. have the parasite. Most of them don't get sick. But the parasite causes serious problems for some people. These include people with weak immune systems and babies whose mothers become infected for the first time during pregnancy.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert B58.89 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
130.7 Toxoplasmosis site NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About B58.89Overview

What is the ICD-10 code for toxoplasmosis with other organ involvement?

The ICD-10-CM code for toxoplasmosis with other organ involvement is B58.89 (sometimes written as B5889). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is B58.89 (Toxoplasmosis with other organ involvement) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report toxoplasmosis with other organ involvement on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does B58.89 group to?

When toxoplasmosis with other organ involvement is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, 974, 976, 975, 867, 869, 868, with relative weights from 0.6784 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.

Is B58.89 a CC or MCC?

CMS lists B58.89 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 9 closely related codes in its exclusion list.

Can B58.89 be reported with P37.1?

Not as a rule. The Excludes1 note at B58, which applies to B58.89, lists "congenital toxoplasmosis (P37.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).