R59.1 - Generalized enlarged lymph nodes

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• Deep lymphadenopathy
• Fibrotic lymphadenopathy
• Generalized enlarged lymph nodes
• Lymphadenopathy
• Lymphadenopathy co-occurrent with human immunodeficiency virus infection
• Paravesicular lymphadenopathy
• Persistent generalized lymphadenopathy
• Piringer-Kuchinka's syndrome
• Postvesicular lymphadenopathy
• Reactive lymphadenopathy
• Superficial lymphadenopathy
• Swelling of lymphoreticular structure
• Tender lymph node
• Tenderness of lymphoreticular structure
• Tethering of lymph node

Clinical Information

• AIDS-Related Complex-. a prodromal phase of infection with the human immunodeficiency virus (hiv). laboratory criteria separating aids-related complex (arc) from aids include elevated or hyperactive b-cell humoral immune responses, compared to depressed or normal antibody reactivity in aids; follicular or mixed hyperplasia in arc lymph nodes, leading to lymphocyte degeneration and depletion more typical of aids; evolving succession of histopathological lesions such as localization of kaposi's sarcoma, signaling the transition to the full-blown aids.
• HIV-. human immunodeficiency virus. a non-taxonomic and historical term referring to any of two species, specifically hiv-1 and/or hiv-2. prior to 1986, this was called human t-lymphotropic virus type iii/lymphadenopathy-associated virus (htlv-iii/lav). from 1986-1990, it was an official species called hiv. since 1991, hiv was no longer considered an official species name; the two species were designated hiv-1 and hiv-2.
• HIV Antibodies-. antibodies reactive with hiv antigens.
• HIV Antigens-. antigens associated with specific proteins of the human adult t-cell immunodeficiency virus (hiv); also called htlv-iii-associated and lymphadenopathy-associated virus (lav) antigens.
• Immunoblastic Lymphadenopathy-. a disorder characterized by proliferation of arborizing small vessels, prominent immunoblastic proliferations and amorphous acidophilic interstitial material. clinical manifestations include fever, sweats, weight loss, generalized lymphadenopathy and frequently hepatosplenomegaly.
• Lymphadenopathy-. disease of lymph nodes which are abnormal in size, number or consistency.
• Spotted Fever Group Rickettsiosis-. a group of arthropod-borne diseases caused by spotted fever bio-group members of rickettsia. they are characterized by fever, headache, and petechial (spotted) rash.
• Lymph Nodes-. they are oval or bean shaped bodies (1 - 30 mm in diameter) located along the lymphatic system.
• Rickettsia-. a genus of gram-negative, aerobic, rod-shaped bacteria often surrounded by a protein microcapsular layer and slime layer. the natural cycle of its organisms generally involves a vertebrate and an invertebrate host. species of the genus are the etiological agents of human diseases, such as typhus.

Diagnostic Related Groups - MS-DRG Mapping

The is diagnosis code is grouped in the following groups for version MS-DRG V40.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC). applicable from 10/01/2022 through 09/30/2023.

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Patient Education

Lymphatic Diseases

The lymphatic system is a network of tissues and organs. It is made up of:

• Lymph - a fluid that contains white blood cells that defend against germs
• Lymph vessels - vessels that carry lymph throughout your body. They are different from blood vessels.
• Lymph nodes - glands found throughout the lymph vessels. Along with your spleen, these nodes are where white blood cells fight infection.

Your bone marrow and thymus produce the cells in lymph. They are part of the system, too.

The lymphatic system clears away infection and keeps your body fluids in balance. If it's not working properly, fluid builds in your tissues and causes swelling, called lymphedema. Other lymphatic system problems can include infections, blockage, and cancer.

Code History

• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)