2027 ICD-10-CM Diagnosis Code B58.1Toxoplasma hepatitis

ICD-10-CM Codes›A00–B99›B50-B64›B58

ICD-10-CM B58.1
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

B58.1 is a billable ICD-10-CM diagnosis code for toxoplasma hepatitis. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 441 through 443, 791, 793, 974 through 976. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 10 closely related codes. Coders also document this condition as acquired disseminated toxoplasmosis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Hepatitis; and Parasitic, other specified and unspecified infections.

Code Identity

ICD-10-CM Code
B58.1
Billable Status
Yes — Valid for Submission
Code Describes
Toxoplasma hepatitis
Short Description
Toxoplasma hepatitis
Same as the full description in the CMS dataset.
Parent Code
Toxoplasmosis

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionB50-B64Protozoal diseases
CategoryB58Toxoplasmosis
This CodeB58.1Toxoplasma hepatitis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acquired disseminated toxoplasmosis
  • Hepatic coccidiosis
  • Hepatitis caused by Toxoplasma gondii
  • Hepatitis due to acquired disseminated toxoplasmosis
  • Multisystemic disseminated toxoplasmosis

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to B58.1: its own notes plus those printed at B58, block B50-B64, and Chapter 1. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From B58 Toxoplasmosis applies to 11 codes
  • infection due to Toxoplasma gondii
From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • diseases generally recognized as communicable or transmissible

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From B58 Toxoplasmosis applies to 11 codes
  • congenital toxoplasmosis (P37.1)
From Block B50-B64 Protozoal diseases applies to 57 codes
  • amebiasis (A06.-)
  • other protozoal intestinal diseases (A07.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • carrier or suspected carrier of infectious disease (Z22.-)
  • certain localized infections - see body system-related chapters
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)
  • influenza and other acute respiratory infections (J00-J22)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • code to identify resistance to antimicrobial drugs (Z16.-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name B58.1, its category, or a range that includes it.

Applicable To 1

These notes mention B58.1.

  • O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium
    Conditions in B50-B64 names B50-B64, which includes this code

Excludes1 1

These codes carry an Excludes1 note naming B58.1: they are not reported together with it, unless the two conditions are unrelated.

  • K77 Liver disorders in diseases classified elsewhere
    toxoplasmosis (acquired) hepatitis (B58.1)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INF007
Hepatitis
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR INF009
Parasitic, other specified and unspecified infections
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Toxoplasma Hepatitis

    hepatitis caused by infection with the protozoan parasite, toxoplasma gondii.
  • Toxoplasmosis

    the acquired form of infection by toxoplasma gondii in animals and man.

Patient EducationClinical

Hepatitis

Hepatitis is inflammation of the liver. Inflammation is swelling that happens when tissues of the body are injured or infected. It can damage your liver. This swelling and damage can affect how well your liver functions.

The full article covers:

  • What is hepatitis?
  • What causes hepatitis?
  • How is viral hepatitis spread?
  • Who is at risk for hepatitis?
  • What are the symptoms of hepatitis?
  • What other problems can hepatitis cause?
  • How is hepatitis diagnosed?
  • What are the treatments for hepatitis?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert B58.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
130.5 Toxoplasma hepatitis
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About B58.1Overview

What is the ICD-10 code for toxoplasma hepatitis?

The ICD-10-CM code for toxoplasma hepatitis is B58.1 (sometimes written as B581). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is B58.1 (Toxoplasmosis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report toxoplasma hepatitis on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does B58.1 group to?

When toxoplasma hepatitis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, 974, 976, 442, 975, 441, 443, with relative weights from 0.6890 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.

Is B58.1 a CC or MCC?

CMS lists B58.1 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 10 closely related codes in its exclusion list.

Can B58.1 be reported with P37.1?

Not as a rule. The Excludes1 note at B58, which applies to B58.1, lists "congenital toxoplasmosis (P37.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).