2026 ICD-10-CM Diagnosis Code B45.8Other forms of cryptococcosis

ICD-10-CM Codes›A00–B99›B35-B49›B45

ICD-10-CM B45.8
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

B45.8 is a billable ICD-10-CM diagnosis code for other forms of cryptococcosis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 867 through 869, 974 through 976. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Fungal infections.

Code Identity

ICD-10-CM Code
B45.8
Billable Status
Yes — Valid for Submission
Code Describes
Other forms of cryptococcosis
Short Description
Other forms of cryptococcosis
Same as the full description in the CMS dataset.
Parent Code
B45
Cryptococcosis

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionB35-B49Mycoses
CategoryB45Cryptococcosis
This CodeB45.8Other forms of cryptococcosis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Cryptococcal chorioretinitis
  • Cryptococcal choroiditis
  • Cryptococcal endophthalmitis
  • Cryptococcal gastroenteritis
  • Cryptococcal retinitis
  • Cryptococcus infection of the central nervous system
  • Cryptococcus neoformans choroiditis
  • Fungal chorioretinitis
  • Fungal choroiditis
  • Fungal endophthalmitis
  • Fungal gastroenteritis
  • Fungal infection of liver
  • Gastritis caused by fungus
  • Hepatic cryptococcosis
  • Ocular cryptococcosis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Cryptococcosis, cryptococcus(infection) (neoformans)
      • specified NEC

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INF004
Fungal infections
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Cryptococcal Gastroenteritis

    gastroenteritis resulting from an infection with cryptosporidium.

  • Fungal Endophthalmitis

    inflammation of the lining of the ocular cavities, which results from a fungal infection.

Patient EducationClinical

Fungal Infections

If you have ever had athlete's foot or a yeast infection, you can blame a fungus. A fungus is a primitive organism. Mushrooms, mold and mildew are examples. Fungi live in air, in soil, on plants and in water. Some live in the human body. Only about half of all types of fungi are harmful.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert B45.8 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
117.5 Cryptococcosis
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About B45.8Overview

Is B45.8 (Cryptococcosis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other forms of cryptococcosis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does B45.8 group to?

When other forms of cryptococcosis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 867, 868, 869, 974, 975, 976, with relative weights from 0.7297 to 2.8860 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of B45.8?

Under the General Equivalence Mappings, other forms of cryptococcosis converts to ICD-9-CM 117.5 (cryptococcosis). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.