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  4. B35-B49
  5. Histoplasmosis (B39)

Histoplasmosis (B39)

The ICD-10 code B39 and its subcodes specifically classify various forms of histoplasmosis, a fungal infection caused by Histoplasma species. These codes help identify different types of histoplasmosis, including pulmonary, disseminated, and African variants, and distinguish between acute, chronic, or unspecified presentations.

This section covers acute and chronic pulmonary histoplasmosis (B39.0 and B39.1), which refer to fungal lung infections often called "pulmonary histoplasmosis." The code B39.3 is for disseminated histoplasmosis, indicating spread beyond the lungs, which may affect the skin and other organs. Code B39.4 addresses histoplasmosis with complications such as retinitis, meningitis, or endocarditis, while B39.5 represents the African histoplasmosis variant (Histoplasmosis duboisii). Lastly, B39.9 is used when histoplasmosis is diagnosed but not specified further. Using these codes accurately supports precise medical documentation and billing for fungal infections caused by Histoplasma, often known as acute pulmonary histoplasmosis, disseminated Histoplasma capsulatum infection, or African histoplasmosis.

Instructional Notations

Code First

Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.

  • associated AIDS B20

Use Additional Code

The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.

  • code for any associated manifestations, such as:
  • endocarditis I39
  • meningitis G02
  • pericarditis I32
  • retinitis H32

Clinical Terms

The following clinical terms provide additional context, helping users better understand the clinical background and common associations for each diagnosis listed in this section. Including related terms alongside ICD-10-CM codes supports coders, billers, and healthcare professionals in improving accuracy, enhancing documentation, and facilitating research or patient education.

Histoplasma

A mitosporic Onygenales fungal genus causing HISTOPLASMOSIS in humans and animals. Its single species is Histoplasma capsulatum which has two varieties: H. capsulatum var. capsulatum and H. capsulatum var. duboisii. Its teleomorph is AJELLOMYCES capsulatus.

Histoplasmosis

Infection resulting from exposure to the fungus HISTOPLASMA.