2026 ICD-10-CM Diagnosis Code B45Cryptococcosis

ICD-10-CM Codes›A00–B99›B35-B49›B45

ICD-10-CM B45
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

B45 is a non-billable ICD-10-CM category code for cryptococcosis, so it cannot be submitted on claims. Use a more specific code from this category instead, such as B45.0, B45.1, B45.2, and B45.3.

Code Identity

ICD-10-CM Code
B45
Billable Status
No — Non-Billable Category
Code Describes
Cryptococcosis
Chapter
B35-B49
Mycoses

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionB35-B49Mycoses
CategoryB45Cryptococcosis
This CodeB45Cryptococcosis

Specific Coding for CryptococcosisOverview

Non-specific codes like B45 require more characters. Use one of these billable codes instead:

  • Use B45.0 for Pulmonary cryptococcosis

  • Use B45.1 for Cerebral cryptococcosis

  • Use B45.2 for Cutaneous cryptococcosis

  • Use B45.3 for Osseous cryptococcosis

  • Use B45.7 for Disseminated cryptococcosis

  • Use B45.8 for Other forms of cryptococcosis

  • Use B45.9 for Cryptococcosis, unspecified

Clinical InformationClinical

  • Cryptococcosis

    fungal infection caused by genus cryptococcus.

  • Meningitis, Cryptococcal

    meningeal inflammation produced by cryptococcus neoformans, an encapsulated yeast that tends to infect individuals with acquired immunodeficiency syndrome and other immunocompromised states. the organism enters the body through the respiratory tract, but symptomatic infections are usually limited to the lungs and nervous system. the organism may also produce parenchymal brain lesions (torulomas). clinically, the course is subacute and may feature headache; nausea; photophobia; focal neurologic deficits; seizures; cranial neuropathies; and hydrocephalus. (from adams et al., principles of neurology, 6th ed, pp721-2)

  • Cryptococcus

    a mitosporic tremellales fungal genus whose species usually have a capsule and do not form pseudomycellium. teleomorphs include filobasidiella and fidobasidium.

  • AIDS-Related Cryptococcosis

    cryptococcosis associated with aids.

  • Cryptococcosis

    an acute or chronic, localized or disseminated infection by cryptococcus neoformans. sites of involvement include the lungs, central nervous system and meninges, skin, and visceral organs.--2004

Patient EducationClinical

Fungal Infections

If you have ever had athlete's foot or a yeast infection, you can blame a fungus. A fungus is a primitive organism. Mushrooms, mold and mildew are examples. Fungi live in air, in soil, on plants and in water. Some live in the human body. Only about half of all types of fungi are harmful.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About B45Overview

Is B45 (Cryptococcosis) a billable code?

No. This is a category header that groups the codes for cryptococcosis, and headers cannot be submitted on claims. Claims for cryptococcosis need a more specific code from this category, such as B45.0, B45.1, and B45.2.