Cryptococcosis (B45) ICD-10-CM
The B45 code range covers cryptococcosis with 8 ICD-10-CM diagnosis codes. 7 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Codes in the B45 Range 8 codes · 7 billable
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the B45 range.
Cryptococcosis
Fungal infection caused by genus CRYPTOCOCCUS.
Cryptococcus
A mitosporic Tremellales fungal genus whose species usually have a capsule and do not form pseudomycellium. Teleomorphs include Filobasidiella and Fidobasidium.
Meningitis, Cryptococcal
Meningeal inflammation produced by CRYPTOCOCCUS NEOFORMANS, an encapsulated yeast that tends to infect individuals with ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunocompromised states. The organism enters the body through the respiratory tract, but symptomatic infections are usually limited to the lungs and nervous system. The organism may also produce parenchymal brain lesions (torulomas). Clinically, the course is subacute and may feature HEADACHE; NAUSEA; PHOTOPHOBIA; focal neurologic deficits; SEIZURES; cranial neuropathies; and HYDROCEPHALUS. (From Adams et al., Principles of Neurology, 6th ed, pp721-2)
About the B45 Code Range
ICD-10 code B45 and its subcodes are used to classify different types of cryptococcosis, a fungal infection caused by Cryptococcus species affecting various body parts.
Cryptococcosis refers to infections coded under B45, with more specific codes for locations like the lungs (B45.0 for pulmonary cryptococcosis), brain (B45.1 for cerebral cryptococcosis, also known as cryptococcal meningitis or cerebral cryptococcoma), skin (B45.2 for cutaneous cryptococcosis or mucocutaneous cryptococcosis), and bones (B45.3 for osseous cryptococcosis). Disseminated cryptococcosis, coded as B45.7 and also called systemic cryptococcosis, covers widespread infection affecting multiple organs. Other forms (B45.8) include fungal infections involving the liver, eyes, or gastrointestinal tract, such as cryptococcal chorioretinitis or fungal gastroenteritis. When the infection site is unspecified, code B45.9 is used, which encompasses cryptococcosis linked to conditions like AIDS. These codes help medical coders accurately capture the disease manifestation and assist healthcare professionals in reporting cryptococcal infections effectively.
Questions About This Page
How many billable codes are in the B45 range?
Of the 8 codes in this range, 7 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the B45 range classify?
The range classifies cryptococcosis. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
