Cryptococcosis (B45)

ICD-10 code B45 and its subcodes are used to classify different types of cryptococcosis, a fungal infection caused by Cryptococcus species affecting various body parts.

Cryptococcosis refers to infections coded under B45, with more specific codes for locations like the lungs (B45.0 for pulmonary cryptococcosis), brain (B45.1 for cerebral cryptococcosis, also known as cryptococcal meningitis or cerebral cryptococcoma), skin (B45.2 for cutaneous cryptococcosis or mucocutaneous cryptococcosis), and bones (B45.3 for osseous cryptococcosis). Disseminated cryptococcosis, coded as B45.7 and also called systemic cryptococcosis, covers widespread infection affecting multiple organs. Other forms (B45.8) include fungal infections involving the liver, eyes, or gastrointestinal tract, such as cryptococcal chorioretinitis or fungal gastroenteritis. When the infection site is unspecified, code B45.9 is used, which encompasses cryptococcosis linked to conditions like AIDS. These codes help medical coders accurately capture the disease manifestation and assist healthcare professionals in reporting cryptococcal infections effectively.

Clinical Terms

The following clinical terms provide additional context, helping users better understand the clinical background and common associations for each diagnosis listed in this section. Including related terms alongside ICD-10-CM codes supports coders, billers, and healthcare professionals in improving accuracy, enhancing documentation, and facilitating research or patient education.

Cryptococcosis

Fungal infection caused by genus CRYPTOCOCCUS.

Cryptococcus

A mitosporic Tremellales fungal genus whose species usually have a capsule and do not form pseudomycellium. Teleomorphs include Filobasidiella and Fidobasidium.

Meningitis, Cryptococcal

Meningeal inflammation produced by CRYPTOCOCCUS NEOFORMANS, an encapsulated yeast that tends to infect individuals with ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunocompromised states. The organism enters the body through the respiratory tract, but symptomatic infections are usually limited to the lungs and nervous system. The organism may also produce parenchymal brain lesions (torulomas). Clinically, the course is subacute and may feature HEADACHE; NAUSEA; PHOTOPHOBIA; focal neurologic deficits; SEIZURES; cranial neuropathies; and HYDROCEPHALUS. (From Adams et al., Principles of Neurology, 6th ed, pp721-2)