2027 ICD-10-CM Diagnosis Code A69.22Other neurologic disorders in Lyme disease

ICD-10-CM Codes›A00–B99›A65-A69›A69

ICD-10-CM A69.22
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

A69.22 is a billable ICD-10-CM diagnosis code for other neurologic disorders in Lyme disease. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 867 through 869. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 56 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Parasitic, other specified and unspecified infections.

Code Identity

ICD-10-CM Code
A69.22
Billable Status
Yes — Valid for Submission
Code Describes
Other neurologic disorders in Lyme disease
Short Description
Other neurologic disorders in Lyme disease
Same as the full description in the CMS dataset.
Parent Code
Lyme disease

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionA65-A69Other spirochetal diseases
CategoryA69Other spirochetal infections
This CodeA69.22Other neurologic disorders in Lyme disease

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Bacterial infection of peripheral nerve
  • Bannwarth syndrome
  • Central nervous system demyelination due to Lyme borreliosis
  • Cranial neuritis caused by Borrelia species
  • Dementia due to Lyme disease
  • Infection of central nervous system caused by Borreliella burgdorferi
  • Lyme mononeuritis multiplex
  • Lyme neuroborreliosis
  • Mononeuritis
  • Mononeuritis multiplex
  • Polyneuropathy caused by Borrelia species

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to A69.22: its own notes plus those printed at block A65-A69 and Chapter 1. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • diseases generally recognized as communicable or transmissible

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Cranial neuritis
  • Meningoencephalitis
  • Polyneuropathy

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block A65-A69 Other spirochetal diseases applies to 28 codes
From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • carrier or suspected carrier of infectious disease (Z22.-)
  • certain localized infections - see body system-related chapters
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)
  • influenza and other acute respiratory infections (J00-J22)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • code to identify resistance to antimicrobial drugs (Z16.-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name A69.22, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming A69.22: they are not reported together with it, unless the two conditions are unrelated.

  • G63 Polyneuropathy in diseases classified elsewhere
    Lyme disease (A69.22)
  • Block L49-L54 Urticaria and erythema
    Lyme disease (A69.2-) names A69.2-, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming A69.22: its condition is not part of those codes, and both may be reported when the patient has both.

  • A68 Relapsing fevers
    Lyme disease (A69.2-) names A69.2-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INF009
Parasitic, other specified and unspecified infections
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Lyme Disease

    an infectious disease caused by a spirochete, borrelia burgdorferi, which is transmitted chiefly by ixodes dammini (see ixodes) and pacificus ticks in the united states and ixodes ricinis (see ixodes) in europe. it is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. the disease was formerly known as lyme arthritis and first discovered at old lyme, connecticut.

Patient EducationClinical

Lyme Disease

Lyme disease is a bacterial infection you get from the bite of an infected tick. At first, Lyme disease usually causes symptoms such as a rash, fever, headache, and fatigue. But if it is not treated early, the infection can spread to your joints, heart, and nervous system. Prompt treatment can help you recover quickly.

The full article covers:

  • What is Lyme disease?
  • What causes Lyme disease?
  • Who is more likely to get Lyme disease?
  • What are the symptoms of Lyme disease?
  • How is Lyme disease diagnosed?
  • What are the treatments for Lyme disease?
  • Can Lyme disease be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert A69.22 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
088.81 Lyme disease
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About A69.22Overview

What is the ICD-10 code for other neurologic disorders in Lyme disease?

The ICD-10-CM code for other neurologic disorders in Lyme disease is A69.22 (sometimes written as A6922). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is A69.22 (Lyme disease) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other neurologic disorders in Lyme disease on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does A69.22 group to?

When other neurologic disorders in Lyme disease is the principal diagnosis on an inpatient stay, it groups to MS-DRG 867, 869, 868, with relative weights from 0.6784 to 2.1855 depending on complications. Higher weights mean higher Medicare reimbursement.

Is A69.22 a CC or MCC?

CMS lists A69.22 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 56 closely related codes in its exclusion list.

What is the ICD-9 equivalent of A69.22?

Under the General Equivalence Mappings, other neurologic disorders in Lyme disease converts to ICD-9-CM 088.81 (Lyme disease). The mapping is approximate, so confirm the match fits the documentation.