2027 ICD-10-CM Diagnosis Code A49.1Streptococcal infection, unspecified site
ICD-10-CM Codes›A00–B99›A30-A49›A49
- Billable — Valid for Submission
- Not Chronic
A49.1 is a billable ICD-10-CM diagnosis code for streptococcal infection, unspecified site. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 867 through 869. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Bacterial infections.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Bacterial infection caused by Streptococcus milleri group
- Drug resistant Streptococcus pneumoniae disease
- Infantile streptococcal infection
- Infection caused by alpha-hemolytic Streptococcus
- Infection caused by beta-hemolytic Streptococcus
- Infection caused by gamma-hemolytic Streptococcus
- Infection caused by Streptococcus gallolyticus
- Infection caused by Streptococcus group D
- Infection caused by Streptococcus group G
- Infection caused by Streptococcus iniae
- Infection caused by Streptococcus mitis group
- Infection caused by Streptococcus suis
- Infection caused by Streptococcus viridans group
- Invasive beta-hemolytic streptococcal disease
- Invasive beta-hemolytic streptococcal disease, non-Group A, non-Group B
- Invasive drug resistant Streptococcus pneumoniae disease
- Invasive streptococcal disease
- Invasive Streptococcus pneumoniae disease
- Neonatal streptococcal infection
- Pneumococcal infectious disease
- Recurrent infection caused by Streptococcus
- Recurrent infection caused by Streptococcus pneumoniae
- Streptococcal infectious disease
- Streptococcus agalactiae infection
- Streptococcus anginosus or Streptococcus dysgalactiae subspecies dysgalactiae
- Streptococcus anginosus or Streptococcus intermedius
- Streptococcus constellatus or Streptococcus anginosus
- Streptococcus group B infection of the infant
- Streptococcus group B infection of the infant - age less than 30 days
- Streptococcus lutetiensis or Streptococcus bovis
- Streptococcus mitis or Streptococcus oralis
- Streptococcus pyogenes infection
- Streptococcus sanguinis or Streptococcus gordonii
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to A49.1: its own notes plus those printed at A49 and Chapter 1. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- diseases generally recognized as communicable or transmissible
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- carrier or suspected carrier of infectious disease (Z22.-)
- certain localized infections - see body system-related chapters
- infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
- infectious and parasitic diseases specific to the perinatal period (P35-P39)
- influenza and other acute respiratory infections (J00-J22)
Use Additional Code
Add a second code, after this one, to fully describe the condition.
- code to identify resistance to antimicrobial drugs (Z16.-)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Streptococcal Infections
infections with bacteria of the genus streptococcus.
Patient EducationClinical
Streptococcal Infections
Strep is short for Streptococcus, a type of bacteria that often lives in your nose and throat. Most strep infections are mild, but some may become serious depending on your overall health.
The full article covers:
- What are streptococcal infections?
- How do streptococcal infections spread?
- Who is more likely to get a streptococcal infection?
- What are the symptoms of streptococcal infections?
- How are streptococcal infections diagnosed?
- What are the treatments for streptococcal infections?
- Can streptococcal infections be prevented?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert A49.1 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About A49.1Overview
What is the ICD-10 code for streptococcal infection, unspecified site?
The ICD-10-CM code for streptococcal infection, unspecified site is A49.1 (sometimes written as A491). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is A49.1 (Bacterial infection of unspecified site) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report streptococcal infection, unspecified site on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does A49.1 group to?
When streptococcal infection, unspecified site is the principal diagnosis on an inpatient stay, it groups to MS-DRG 867, 869, 868, with relative weights from 0.6784 to 2.1855 depending on complications. Higher weights mean higher Medicare reimbursement.
Can A49.1 be reported with A39.9?
Not as a rule. The Excludes1 note at A49, which applies to A49.1, lists "meningococcal infection NOS (A39.9)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What is the ICD-9 equivalent of A49.1?
Under the General Equivalence Mappings, streptococcal infection, unspecified site converts to ICD-9-CM 041.00 (Streptococcus unspecf). The mapping is approximate, so confirm the match fits the documentation.
