2027 ICD-10-CM Diagnosis Code A06.81Amebic cystitis

ICD-10-CM Codes›A00–B99›A00-A09›A06

ICD-10-CM A06.81
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

A06.81 is a billable ICD-10-CM diagnosis code for amebic cystitis. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 867 through 869. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 10 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Parasitic, other specified and unspecified infections.

Code Identity

ICD-10-CM Code
A06.81
Billable Status
Yes — Valid for Submission
Code Describes
Amebic cystitis
Short Description
Amebic cystitis
Same as the full description in the CMS dataset.
Parent Code
Amebic infection of other sites

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionA00-A09Intestinal infectious diseases
CategoryA06Amebiasis
This CodeA06.81Amebic cystitis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Amebic cystitis

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to A06.81: its own notes plus those printed at A06 and Chapter 1. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From A06 Amebiasis applies to 12 codes
  • infection due to Entamoeba histolytica
From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • diseases generally recognized as communicable or transmissible

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From A06 Amebiasis applies to 12 codes
  • other protozoal intestinal diseases (A07.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From A06 Amebiasis applies to 12 codes
From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • carrier or suspected carrier of infectious disease (Z22.-)
  • certain localized infections - see body system-related chapters
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)
  • influenza and other acute respiratory infections (J00-J22)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • code to identify resistance to antimicrobial drugs (Z16.-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name A06.81, its category, or a range that includes it.

Excludes1 3

These codes carry an Excludes1 note naming A06.81: they are not reported together with it, unless the two conditions are unrelated.

  • Block B50-B64 Protozoal diseases
    amebiasis (A06.-) names A06.-, which includes this code
  • N48.1 Balanitis
    amebic balanitis (A06.8) names A06.8, which includes this code
  • N51 Disorders of male genital organs in diseases classified elsewhere
    amebic balanitis (A06.8) names A06.8, which includes this code

Excludes2 2

These codes carry an Excludes2 note naming A06.81: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block P35-P39 Infections specific to the perinatal period
    intestinal infectious disease (A00-A09) names A00-A09, which includes this code
  • P37 Other congenital infectious and parasitic diseases
    infectious neonatal diarrhea (A00-A09) names A00-A09, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INF009
Parasitic, other specified and unspecified infections
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Amebiasis

    infection with any of various amebae. it is an asymptomatic carrier state in most individuals, but diseases ranging from chronic, mild diarrhea to fulminant dysentery may occur.

Patient EducationClinical

Parasitic Diseases

Parasites are living things that use other living things - like your body - for food and a place to live. You can get them from contaminated food or water, a bug bite, or sexual contact. Some parasitic diseases are easily treated and some are not.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert A06.81 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
006.8 Amebic infection NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About A06.81Overview

What is the ICD-10 code for amebic cystitis?

The ICD-10-CM code for amebic cystitis is A06.81 (sometimes written as A0681). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is A06.81 (Amebic infection of other sites) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report amebic cystitis on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does A06.81 group to?

When amebic cystitis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 867, 869, 868, with relative weights from 0.6784 to 2.1855 depending on complications. Higher weights mean higher Medicare reimbursement.

Is A06.81 a CC or MCC?

CMS lists A06.81 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 10 closely related codes in its exclusion list.

Can A06.81 be reported with a code from A07?

Not as a rule. The Excludes1 note at A06, which applies to A06.81, lists "other protozoal intestinal diseases (A07.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).