Cholera (A00) ICD-10-CM
The A00 code range covers cholera with 4 ICD-10-CM diagnosis codes. 3 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Codes in the A00 Range 4 codes · 3 billable
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the A00 range.
Cholera
An acute diarrheal disease endemic in India and Southeast Asia whose causative agent is VIBRIO CHOLERAE. This condition can lead to severe dehydration in a matter of hours unless quickly treated.
Cholera Morbus
An old term that is no longer used in the scientific literature. Cholera morbus refers to acute GASTROENTERITIS occurring in summer or autumn; characterized by severe cramps, diarrhea, and vomiting.
Cholera Toxin
An ENTEROTOXIN from VIBRIO CHOLERAE. It consists of two major protomers, the heavy (H) or A subunit and the B protomer which consists of 5 light (L) or B subunits. The catalytic A subunit is proteolytically cleaved into fragments A1 and A2. The A1 fragment is a MONO(ADP-RIBOSE) TRANSFERASE. The B protomer binds cholera toxin to intestinal epithelial cells and facilitates the uptake of the A1 fragment. The A1 catalyzed transfer of ADP-RIBOSE to the alpha subunits of heterotrimeric G PROTEINS activates the production of CYCLIC AMP. Increased levels of cyclic AMP are thought to modulate release of fluid and electrolytes from intestinal crypt cells.
Cholera Vaccines
Vaccines or candidate vaccines used to prevent infection with VIBRIO CHOLERAE. The original cholera vaccine consisted of killed bacteria, but other kinds of vaccines now exist.
Classical Swine Fever
An acute, highly contagious disease affecting swine of all ages and caused by the CLASSICAL SWINE FEVER VIRUS. It has a sudden onset with high morbidity and mortality.
Classical Swine Fever Virus
A species of the PESTIVIRUS genus causing exceedingly contagious and fatal hemorrhagic disease of swine.
Gastroenteritis
INFLAMMATION of any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Causes of gastroenteritis are many including genetic, infection, HYPERSENSITIVITY, drug effects, and CANCER.
Gastrointestinal Diseases
Diseases in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.
Pestivirus
A genus of FLAVIVIRIDAE, also known as mucosal disease virus group, which is not arthropod-borne. Transmission is by direct and indirect contact, and by transplacental and congenital transmission. Species include BORDER DISEASE VIRUS, bovine viral diarrhea virus (DIARRHEA VIRUS, BOVINE VIRAL), and CLASSICAL SWINE FEVER VIRUS.
Vibrio cholerae
The etiologic agent of CHOLERA.
Vipoma
A tumor that secretes VASOACTIVE INTESTINAL PEPTIDE, a neuropeptide that causes VASODILATION; relaxation of smooth muscles; watery DIARRHEA; HYPOKALEMIA; and HYPOCHLORHYDRIA. Vipomas, derived from the pancreatic ISLET CELLS, generally are malignant and can secrete other hormones. In most cases, Vipomas are located in the PANCREAS but can be found in extrapancreatic sites.
About the A00 Code Range
ICD-10 code A00 is used to classify cholera, an acute intestinal infection caused by Vibrio cholerae bacteria. This section breaks down cholera into specific types based on the bacterial strain responsible for the disease.
The codes under the A00 category help medical coders accurately report different forms of cholera. For example, A00.0 pertains to cholera caused by Vibrio cholerae O1 classical biotype, sometimes referred to as "Cholera caused by Vibrio cholerae O1 Classical biotype." Similarly, A00.1 identifies cholera due to the O1 El Tor biovar, which is an alternate strain, often called "Cholera caused by Vibrio cholerae El Tor." When the specific bacterial strain is not identified or if it involves other groups like non-O1 or O139, coders use A00.9, labeled as "Cholera, unspecified." This includes infections sometimes described as Vibrio cholerae enteritis of the intestine. Using these precise ICD-10 codes ensures correct tracking and treatment documentation for cholera cases at healthcare facilities.
Questions About This Page
How many billable codes are in the A00 range?
Of the 4 codes in this range, 3 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the A00 range classify?
The range classifies cholera. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
