2027 ICD-10-CM Diagnosis Code Z52.001Unspecified donor, stem cells

ICD-10-CM Codes›Z00–Z99›Z40-Z53›Z52

ICD-10-CM Z52.001
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

Z52.001 is a billable ICD-10-CM diagnosis code for unspecified donor, stem cells. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 951. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified status.

Code Identity

ICD-10-CM Code
Z52.001
Billable Status
Yes — Valid for Submission
Code Describes
Unspecified donor, stem cells
Short Description
Unspecified donor, stem cells
Same as the full description in the CMS dataset.
Parent Code
Z52.00
Unspecified blood donor

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ40-Z53Encounters for other specific health care
CategoryZ52Donors of organs and tissues
This CodeZ52.001Unspecified donor, stem cells

Present on Admission (POA)Billing

Z52.001 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review the other POA exempt codes in Encounters for other specific health care (Z40-Z53).

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to Z52.001: its own notes plus those printed at Z52, block Z40-Z53, and Chapter 21. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Z52 Donors of organs and tissues applies to 26 codes
  • autologous and other living donors

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Z52 Donors of organs and tissues applies to 26 codes
  • cadaveric donor - omit code
  • examination of potential donor (Z00.5)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block Z40-Z53 Encounters for other specific health care applies to 164 codes
  • follow-up examination for medical surveillance after treatment (Z08-Z09)

Notes

General instructions on how these codes are used.

From Chapter 21 (Z00-Z99) Factors influencing health status and contact with health services applies to 1,425 codes
  • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
  • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
  • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name Z52.001, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming Z52.001: they are not reported together with it, unless the two conditions are unrelated.

  • Z40 Encounter for prophylactic surgery
    organ donations (Z52.-) names Z52.-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR FAC025
Other specified status
Default principal diagnosis: inpatient No · outpatient Yes

Patient EducationClinical

Stem Cells

Stem cells are cells with the potential to develop into many different types of cells in the body. They serve as a repair system for the body. There are two main types of stem cells: embryonic stem cells and adult stem cells.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert Z52.001 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
V59.02 Blood donor-stem cells
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About Z52.001Overview

What is the ICD-10 code for unspecified donor, stem cells?

The ICD-10-CM code for unspecified donor, stem cells is Z52.001 (sometimes written as Z52001). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is Z52.001 (Unspecified blood donor) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report unspecified donor, stem cells on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does Z52.001 group to?

When unspecified donor, stem cells is the principal diagnosis on an inpatient stay, it groups to MS-DRG 951 (other Factors Influencing Health Status), which carries a relative weight of 0.5574. Higher weights mean higher Medicare reimbursement.

Is Z52.001 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for unspecified donor, stem cells on inpatient claims. The code appears in the Encounters for other specific health care (Z40-Z53) range of the CMS exempt list.

Can Z52.001 be reported with Z00.5?

Not as a rule. The Excludes1 note at Z52, which applies to Z52.001, lists "examination of potential donor (Z00.5)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).