2026 ICD-10-CM Diagnosis Code Z00.6Encounter for examination for normal comparison and control in clinical research program

ICD-10-CM Codes›Z00–Z99›Z00-Z13›Z00

ICD-10-CM Z00.6
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Z00.6 is a billable ICD-10-CM diagnosis code for encounter for examination for normal comparison and control in clinical research program. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Medical examination/evaluation.

Code Identity

ICD-10-CM Code
Z00.6
Billable Status
Yes — Valid for Submission
Code Describes
Encounter for examination for normal comparison and control in clinical research program
Short Description
Encntr for exam for nrml cmprsn and ctrl in clncl rsrch prog
Parent Code
Z00
Encounter for general examination without complaint, suspected or reported diagnosis

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ00-Z13Persons encountering health services for examinations
CategoryZ00Encounter for general examination without complaint, suspected or reported diagnosis
This CodeZ00.6Encounter for examination for normal comparison and control in clinical research program

Present on Admission (POA)Billing

Z00.6 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Examination of participant or control in clinical research program

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Admission(for)
      • clinical research investigation (control) (normal comparison) (participant)
    • Admission(for)
      • examination at health care facility (adult)
        • clinical research investigation (control) (normal comparison) (participant)
    • Clinical research investigation(clinical trial) (control subject) (normal comparison) (participant)
    • Examination(for) (following) (general) (of) (routine)
      • clinical research control or normal comparison (control) (participant)
    • Examination(for) (following) (general) (of) (routine)
      • medical (adult) (for) (of)
        • clinical research, normal subject (control) (participant)
    • Examination(for) (following) (general) (of) (routine)
      • medical (adult) (for) (of)
        • control subject in clinical research (normal comparison) (participant)
    • Investigation
      • clinical research subject (control) (normal comparison) (participant)
    • Person(with)
      • admitted for clinical research, as a control subject (normal comparison) (participant)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR FAC014
Medical examination/evaluation
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Clinical Trials

Clinical trials are research studies that test how well new medical approaches work in people. Each study answers scientific questions and tries to find better ways to prevent, screen for, diagnose, or treat a disease. Clinical trials may also compare a new treatment to a treatment that is already available.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert Z00.6 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
V70.7 Exam-clincal trial
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Z00.6Overview

Is Z00.6 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report encounter for examination for normal comparison and control in clinical research program on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Is Z00.6 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for encounter for examination for normal comparison and control in clinical research program on inpatient claims.

What is the ICD-9 equivalent of Z00.6?

Under the General Equivalence Mappings, encounter for examination for normal comparison and control in clinical research program converts to ICD-9-CM V70.7 (exam-clincal trial). The mapping is a direct match.