2027 ICD-10-CM Diagnosis Code T54.3X4SToxic effect of corrosive alkalis and alkali-like substances, undetermined, sequela

ICD-10-CM Codes›S00–T88›T51-T65›T54

ICD-10-CM T54.3X4S
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

T54.3X4S is a billable ICD-10-CM diagnosis code for toxic effect of corrosive alkalis and alkali-like substances, undetermined, sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 922 through 923. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Poisoning/toxic effect/adverse effects/underdosing, sequela.

Code Identity

ICD-10-CM Code
T54.3X4S
Billable Status
Yes — Valid for Submission
Code Describes
Toxic effect of corrosive alkalis and alkali-like substances, undetermined, sequela
Short Description
Tox eff of corrosv alkalis and alk-like substnc, undet, sqla
Parent Code
Toxic effect of corrosive alkalis and alkali-like substances, undetermined

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT51-T65Toxic effects of substances chiefly nonmedicinal as to source
CategoryT54Toxic effect of corrosive substances
This CodeT54.3X4SToxic effect of corrosive alkalis and alkali-like substances, undetermined, sequela

Present on Admission (POA)Billing

T54.3X4S is exempt from POA reporting on inpatient claims to general acute care hospitals. Review the other POA exempt codes in Toxic effects of substances chiefly nonmedicinal as to source (T51-T65).

Coding GuidelinesGuidance

The appropriate 7th character is to be added to each code from block Toxic effect of corrosive substances (T54). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027, published by CMS and the National Center for Health Statistics.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to T54.3X4S: its own notes plus those printed at T54, block T51-T65, and Chapter 19. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block T51-T65 Toxic effects of substances chiefly nonmedicinal as to source applies to 1,680 codes
  • contact with and (suspected) exposure to toxic substances (Z77.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Block T51-T65 Toxic effects of substances chiefly nonmedicinal as to source applies to 1,680 codes
  • code(s):
  • for all associated manifestations of toxic effect, such as: respiratory conditions due to external agents (J60-J70)
  • personal history of foreign body fully removed (Z87.821)
  • to identify any retained foreign body, if applicable (Z18.-)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • code to identify any retained foreign body, if applicable (Z18.-)

Notes

General instructions on how these codes are used.

From Block T51-T65 Toxic effects of substances chiefly nonmedicinal as to source applies to 1,680 codes
  • When no intent is indicated code to accidental. Undetermined intent is only for use when there is specific documentation in the record that the intent of the toxic effect cannot be determined.
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
  • The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.

7th Character

Every code in the category takes a 7th character from the listed values, with the placeholder X filling any empty positions before it.

From T54 Toxic effect of corrosive substances applies to 60 codes
  • The appropriate 7th character is to be added to each code from category T54
  • Ainitial encounter
  • Dsubsequent encounter
  • Ssequela this code

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ075
Poisoning/toxic effect/adverse effects/underdosing, sequela
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Alkalies

    usually a hydroxide of lithium, sodium, potassium, rubidium or cesium, but also the carbonates of these metals, ammonia, and the amines. (grant & hackh's chemical dictionary, 5th ed)
  • Lye

    generally speaking, it is the alkaline substance obtained from wood ashes by percolation. preparations of lye can be solutions of either potassium or sodium hydroxide. the term lye, is also used to refer to the household product which is a mixture of sodium hydroxide and sodium carbonate.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
Alkali (caustic)T54.3X1T54.3X2T54.3X3T54.3X4––
Ammonia (fumes) (gas) (vapor)::liquid (household)T54.3X1T54.3X2T54.3X3T54.3X4––
Ammonium::carbonateT54.3X1T54.3X2T54.3X3T54.3X4––
Ammonium::compounds (household) NECT54.3X1T54.3X2T54.3X3T54.3X4––
Ammonium::compounds (household) NEC::industrialT54.3X1T54.3X2T54.3X3T54.3X4––
Calcium::hydrate, hydroxideT54.3X1T54.3X2T54.3X3T54.3X4––
Calcium::hypochloriteT54.3X1T54.3X2T54.3X3T54.3X4––
Calcium::oxideT54.3X1T54.3X2T54.3X3T54.3X4––
Caustic (s) NEC::alkaliT54.3X1T54.3X2T54.3X3T54.3X4––
Caustic (s) NEC::hydroxideT54.3X1T54.3X2T54.3X3T54.3X4––
Caustic (s) NEC::potashT54.3X1T54.3X2T54.3X3T54.3X4––
Caustic (s) NEC::sodaT54.3X1T54.3X2T54.3X3T54.3X4––
Chloride of lime (bleach)T54.3X1T54.3X2T54.3X3T54.3X4––
Chlorinated::lime (bleach)T54.3X1T54.3X2T54.3X3T54.3X4––
Chlorine (fumes) (gas)::bleachT54.3X1T54.3X2T54.3X3T54.3X4––
Disinfectant::alkalineT54.3X1T54.3X2T54.3X3T54.3X4––
Drano (drain cleaner)T54.3X1T54.3X2T54.3X3T54.3X4––
Hydroxide, causticT54.3X1T54.3X2T54.3X3T54.3X4––
Lime (chloride)T54.3X1T54.3X2T54.3X3T54.3X4––
Lye (concentrated)T54.3X1T54.3X2T54.3X3T54.3X4––
Potash (caustic)T54.3X1T54.3X2T54.3X3T54.3X4––
Potassium (salts) NEC::carbonateT54.3X1T54.3X2T54.3X3T54.3X4––
Potassium (salts) NEC::hydroxideT54.3X1T54.3X2T54.3X3T54.3X4––
QuicklimeT54.3X1T54.3X2T54.3X3T54.3X4––
Soda (caustic)T54.3X1T54.3X2T54.3X3T54.3X4––
Sodium::carbonate NECT54.3X1T54.3X2T54.3X3T54.3X4––
Sodium::hydroxideT54.3X1T54.3X2T54.3X3T54.3X4––
Sodium::hypochlorite (bleach) NECT54.3X1T54.3X2T54.3X3T54.3X4––
Sodium::hypochlorite (bleach) NEC::disinfectantT54.3X1T54.3X2T54.3X3T54.3X4––
Sodium::hypochlorite (bleach) NEC::vaporT54.3X1T54.3X2T54.3X3T54.3X4––
Triethanolamine NECT54.3X1T54.3X2T54.3X3T54.3X4––
Triethanolamine NEC::detergentT54.3X1T54.3X2T54.3X3T54.3X4––

Convert T54.3X4S to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
909.1 Late eff nonmed substanc
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About T54.3X4SOverview

Is T54.3X4S a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report toxic effect of corrosive alkalis and alkali-like substances, undetermined, sequela on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What does the 7th character S in T54.3X4S mean?

The final character S makes this a sequela code: it reports a lingering problem that remains after the toxic effect of corrosive alkalis and alkali-like substances, undetermined itself has resolved, not the original event.

What MS-DRG does T54.3X4S group to?

When toxic effect of corrosive alkalis and alkali-like substances, undetermined, sequela is the principal diagnosis on an inpatient stay, it groups to MS-DRG 923, 922, with relative weights from 0.9980 to 1.6248 depending on complications. Higher weights mean higher Medicare reimbursement.

Is T54.3X4S exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for toxic effect of corrosive alkalis and alkali-like substances, undetermined, sequela on inpatient claims. The code appears in the Toxic effects of substances chiefly nonmedicinal as to source (T51-T65) range of the CMS exempt list.

Can T54.3X4S be reported with a code from Z77?

Not as a rule. The Excludes1 note at block T51-T65, which applies to T54.3X4S, lists "contact with and (suspected) exposure to toxic substances (Z77.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).