2026 ICD-10-CM Diagnosis Code T53.1X1SToxic effect of chloroform, accidental (unintentional), sequela

ICD-10-CM CodesS00–T88T51-T65T53

ICD-10-CM T53.1X1S
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T53.1X1S is a billable ICD-10-CM diagnosis code for toxic effect of chloroform, accidental (unintentional), sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 922 through 923. The code is exempt from POA reporting. Coders also document this condition as chloroform poisoning. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Poisoning/toxic effect/adverse effects/underdosing, sequela.

Code Identity

ICD-10-CM Code
T53.1X1S
Billable Status
Yes — Valid for Submission
Code Describes
Toxic effect of chloroform, accidental (unintentional), sequela
Short Description
Toxic effect of chloroform, accidental, sequela
Parent Code
Toxic effect of chloroform, accidental (unintentional)

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT51-T65Toxic effects of substances chiefly nonmedicinal as to source
CategoryT53Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbons
This CodeT53.1X1SToxic effect of chloroform, accidental (unintentional), sequela

Present on Admission (POA)Billing

T53.1X1S is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Chloroform poisoning

Coding GuidelinesGuidance

The appropriate 7th character is to be added to each code from block Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbons (T53). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ075
Poisoning/toxic effect/adverse effects/underdosing, sequela
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
Chloroform (fumes) (vapor)T53.1X1T53.1X2T53.1X3T53.1X4
Chloroform (fumes) (vapor)::anestheticT53.1X1T53.1X2T53.1X3T53.1X4
Chloroform (fumes) (vapor)::solventT53.1X1T53.1X2T53.1X3T53.1X4
Chloroform (fumes) (vapor)::water, concentratedT53.1X1T53.1X2T53.1X3T53.1X4

Convert T53.1X1S to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
909.1 Late eff nonmed substanc
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T53.1X1SOverview

Is T53.1X1S (Toxic effect of chloroform, accidental (unintentional)) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report toxic effect of chloroform, accidental (unintentional), sequela on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character S in T53.1X1S mean?

The final character S makes this a sequela code: it reports a lingering problem that remains after the toxic effect of chloroform, accidental (unintentional) itself has resolved, not the original event.

What MS-DRG does T53.1X1S group to?

When toxic effect of chloroform, accidental (unintentional), sequela is the principal diagnosis on an inpatient stay, it groups to MS-DRG 922, 923, with relative weights from 1.0177 to 1.7494 depending on complications. Higher weights mean higher Medicare reimbursement.

Is T53.1X1S exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for toxic effect of chloroform, accidental (unintentional), sequela on inpatient claims.

What is the ICD-9 equivalent of T53.1X1S?

Under the General Equivalence Mappings, toxic effect of chloroform, accidental (unintentional), sequela converts to ICD-9-CM 909.1 (late eff nonmed substanc). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.