2026 ICD-10-CM Diagnosis Code T52.4X1AToxic effect of ketones, accidental (unintentional), initial encounter
T52.4X1A is a billable ICD-10-CM diagnosis code for toxic effect of ketones, accidental (unintentional), initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 917 through 918. Coders also document this condition as toxic effect of acetone. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, accidental/unintentional; External cause codes: poisoning by non-drug; and Toxic effects, initial encounter.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Toxic effect of acetone
Coding GuidelinesGuidance
The appropriate 7th character is to be added to each code from block Toxic effect of organic solvents (T52). Use the following options for the applicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Table of Drugs and ChemicalsClinical
Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.
| Substance | Accidental | Self-harm | Assault | Undetermined | Adverse Effect | Underdosing |
|---|---|---|---|---|---|---|
| Acetone (oils) | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Acetone (oils)::chlorinated | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Acetone (oils)::vapor | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Acetophenone | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Butanone, 2-butanone | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Cyclohexanone | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Diacetone alcohol | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Hexanone, 2-hexanone | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Hexone | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Hydroxymethylpentanone | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Ketols | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Ketone oils | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| MEK (methyl ethyl ketone) | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::acetate | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::acetone | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::acrylate | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::alcohol | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::aminophenol | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::amphetamine | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::androstanolone | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::atropine | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::benzene | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::benzoate | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::benzol | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::bromide (gas) | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::bromide (gas)::fumigant | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::butanol | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::carbinol | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::carbonate | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::CCNU | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::cellosolve | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::cellulose | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::chloride (gas) | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::chloroformate | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::cyclohexane | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::cyclohexanol | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::cyclohexanone | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::cyclohexyl acetate | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::demeton | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::dihydromorphinone | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::ergometrine | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::ergonovine | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::ethyl ketone | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::glucamine antimonate | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::hydrazine | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::iodide | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::isobutyl ketone | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::isothiocyanate | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::mercaptan | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::morphine NEC | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::nicotinate | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::paraben | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::parafynol | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::parathion | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::peridol | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::phenidate | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::prednisolone | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::prednisolone::ENT agent | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::prednisolone::ophthalmic preparation | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::prednisolone::topical NEC | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::propylcarbinol | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::rosaniline NEC | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::salicylate | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::sulfate (fumes) | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::sulfate (fumes)::liquid | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::sulfonal | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::testosterone | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
| Methyl::thiouracil | T52.4X1 | T52.4X2 | T52.4X3 | T52.4X4 | – | – |
Convert T52.4X1A to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About T52.4X1AOverview
Is T52.4X1A (Toxic effect of ketones, accidental (unintentional)) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report toxic effect of ketones, accidental (unintentional), initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What does the 7th character A in T52.4X1A mean?
The final character A marks the initial encounter: use it while the patient is receiving active treatment for toxic effect of ketones, accidental (unintentional), such as an emergency visit or first evaluation.
What MS-DRG does T52.4X1A group to?
When toxic effect of ketones, accidental (unintentional), initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 917, 918, with relative weights from 0.8571 to 1.5684 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of T52.4X1A?
Under the General Equivalence Mappings, toxic effect of ketones, accidental (unintentional), initial encounter converts to ICD-9-CM 982.8 (toxic eff nonpetrol solv) and E862.4 (acc poisn-solvents NEC). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
