2026 ICD-10-CM Diagnosis Code T52.2X4SToxic effect of homologues of benzene, undetermined, sequela

ICD-10-CM CodesS00–T88T51-T65T52

ICD-10-CM T52.2X4S
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T52.2X4S is a billable ICD-10-CM diagnosis code for toxic effect of homologues of benzene, undetermined, sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 922 through 923. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Poisoning/toxic effect/adverse effects/underdosing, sequela.

Code Identity

ICD-10-CM Code
T52.2X4S
Billable Status
Yes — Valid for Submission
Code Describes
Toxic effect of homologues of benzene, undetermined, sequela
Short Description
Toxic effect of homologues of benzene, undetermined, sequela
Same as the full description in the CMS dataset.
Parent Code
Toxic effect of homologues of benzene, undetermined

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT51-T65Toxic effects of substances chiefly nonmedicinal as to source
CategoryT52Toxic effect of organic solvents
This CodeT52.2X4SToxic effect of homologues of benzene, undetermined, sequela

Present on Admission (POA)Billing

T52.2X4S is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Coding GuidelinesGuidance

The appropriate 7th character is to be added to each code from block Toxic effect of organic solvents (T52). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ075
Poisoning/toxic effect/adverse effects/underdosing, sequela
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hexylresorcinol

    a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
ButyltolueneT52.2X1T52.2X2T52.2X3T52.2X4
HexylresorcinolT52.2X1T52.2X2T52.2X3T52.2X4
HydroquinoneT52.2X1T52.2X2T52.2X3T52.2X4
Hydroquinone::vaporT52.2X1T52.2X2T52.2X3T52.2X4
Toluene (liquid)T52.2X1T52.2X2T52.2X3T52.2X4
Toluene (liquid)::diisocyanateT52.2X1T52.2X2T52.2X3T52.2X4
Toluol (liquid)T52.2X1T52.2X2T52.2X3T52.2X4
Toluol (liquid)::vaporT52.2X1T52.2X2T52.2X3T52.2X4
Xylene (vapor)T52.2X1T52.2X2T52.2X3T52.2X4
Xylol (vapor)T52.2X1T52.2X2T52.2X3T52.2X4

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T52.2X4S to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
909.1 Late eff nonmed substanc
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T52.2X4SOverview

Is T52.2X4S (Toxic effect of homologues of benzene, undetermined) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report toxic effect of homologues of benzene, undetermined, sequela on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character S in T52.2X4S mean?

The final character S makes this a sequela code: it reports a lingering problem that remains after the toxic effect of homologues of benzene, undetermined itself has resolved, not the original event.

What MS-DRG does T52.2X4S group to?

When toxic effect of homologues of benzene, undetermined, sequela is the principal diagnosis on an inpatient stay, it groups to MS-DRG 922, 923, with relative weights from 1.0177 to 1.7494 depending on complications. Higher weights mean higher Medicare reimbursement.

Is T52.2X4S exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for toxic effect of homologues of benzene, undetermined, sequela on inpatient claims.

What is the ICD-9 equivalent of T52.2X4S?

Under the General Equivalence Mappings, toxic effect of homologues of benzene, undetermined, sequela converts to ICD-9-CM 909.1 (late eff nonmed substanc). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.