2026 ICD-10-CM Diagnosis Code T52.1X2AToxic effect of benzene, intentional self-harm, initial encounter

ICD-10-CM CodesS00–T88T51-T65T52

ICD-10-CM T52.1X2A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T52.1X2A is a billable ICD-10-CM diagnosis code for toxic effect of benzene, intentional self-harm, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 917 through 918. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, self-harm; External cause codes: poisoning by non-drug; and Suicidal ideation/attempt/intentional self-harm.

Code Identity

ICD-10-CM Code
T52.1X2A
Billable Status
Yes — Valid for Submission
Code Describes
Toxic effect of benzene, intentional self-harm, initial encounter
Short Description
Toxic effect of benzene, intentional self-harm, init encntr
Parent Code
Toxic effect of benzene, intentional self-harm

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT51-T65Toxic effects of substances chiefly nonmedicinal as to source
CategoryT52Toxic effect of organic solvents
This CodeT52.1X2AToxic effect of benzene, intentional self-harm, initial encounter

Coding GuidelinesGuidance

The appropriate 7th character is to be added to each code from block Toxic effect of organic solvents (T52). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EXT021
External cause codes: intent of injury, self-harm
Default principal diagnosis: inpatient No · outpatient No
CCSR EXT015
External cause codes: poisoning by non-drug
Default principal diagnosis: inpatient No · outpatient No
CCSR MBD012
Suicidal ideation/attempt/intentional self-harm
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR INJ023
Toxic effects, initial encounter
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer

    a non-peptide, kappa-opioid receptor agonist which has also been found to stimulate the release of adrenocorticotropin (adrenocorticotropic hormone) via the release of hypothalamic arginine vasopressin (arginine vasopressin) and corticotropin-releasing hormone. (from j pharmacol exp ther 1997;280(1):416-21)
  • Benzene

    toxic, volatile, flammable liquid hydrocarbon byproduct of coal distillation. it is used as an industrial solvent in paints, varnishes, lacquer thinners, gasoline, etc. benzene causes central nervous system damage acutely and bone marrow damage chronically and is carcinogenic. it was formerly used as parasiticide.
  • Benzene Derivatives

    organic compounds derived from benzene.
  • Benzeneacetamides

    compounds based on benzeneacetamide, that are similar in structure to acetanilides.
  • Benzenesulfonamides

    a group of compounds that contain sulfonamide group s-linked to a benzene ring. many benzenesulfonamide derivatives are pharmaceuticals (e.g., bosentan; sulfapyridine; and sulfadiazine; celecoxib) as their sulfonamide moiety target various enzymes (e.g., carbonic anhydrases; acetylcholinesterase; butyrylcholinesterase; and cyclooxynenase 2).
  • Benzenesulfonates

    organic salts and esters of benzenesulfonic acid.
  • Benzyl Alcohol

    a colorless liquid with a sharp burning taste and slight odor. it is used as a local anesthetic and to reduce pain associated with lidocaine injection. also, it is used in the manufacture of other benzyl compounds, as a pharmaceutic aid, and in perfumery and flavoring.
  • Benzylammonium Compounds

    quaternary ammonium compounds based on benzylamines with the general formula phenyl-cn+r3.
  • Dichlorodiphenyl Dichloroethylene

    an organochlorine pesticide, it is the ethylene metabolite of ddt.
  • Dinitrochlorobenzene

    a skin irritant that may cause dermatitis of both primary and allergic types. contact sensitization with dncb has been used as a measure of cellular immunity. dncb is also used as a reagent for the detection and determination of pyridine compounds.
  • Hexachlorocyclohexane

    any of several polyhalogenated organic compounds consisting of a six-carbon ring with one chlorine and one hydrogen attached to each carbon.
  • Ibuprofen

    a non-steroidal anti-inflammatory agent with analgesic, antipyretic, and anti-inflammatory properties
  • Ipodate

    ionic monomeric contrast media. usually the sodium or calcium salts are used for examination of the gall bladder and biliary tract. (from martindale, the extra pharmacopoeia, 30th ed, p704)
  • Phenylacetates

    derivatives of phenylacetic acid. included under this heading are a variety of acid forms, salts, esters, and amides that contain the benzeneacetic acid structure. note that this class of compounds should not be confused with derivatives of phenyl acetate, which contain the phenol ester of acetic acid.
  • Phenylmethylsulfonyl Fluoride

    an enzyme inhibitor that inactivates irc-50 arvin, subtilisin, and the fatty acid synthetase complex.
  • Phloroglucinol

    a trinitrobenzene derivative with antispasmodic properties that is used primarily as a laboratory reagent.
  • Sulfamethazine

    a sulfanilamide anti-infective agent. it has a spectrum of antimicrobial action similar to other sulfonamides.
  • Sulfathiazole

    a sulfathiazole compound that is used as a short-acting anti-infective agent. it is no longer commonly used systemically due to its toxicity, but may still be applied topically in combination with other drugs for the treatment of vaginal and skin infections, and is still used in veterinary medicine.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
BenzeneT52.1X1T52.1X2T52.1X3T52.1X4
Benzene::homologues (acetyl) (dimethyl) (methyl) (solvent)T52.1X1T52.1X2T52.1X3T52.1X4
Benzol (benzene)T52.1X1T52.1X2T52.1X3T52.1X4
Benzol (benzene)::vaporT52.1X1T52.1X2T52.1X3T52.1X4
Diphenylmethane dyeT52.1X1T52.1X2T52.1X3T52.1X4

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T52.1X2A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
982.0 Toxic effect benzene
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E950.9 Poison-solid/liquid NEC
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T52.1X2AOverview

Is T52.1X2A (Toxic effect of benzene, intentional self-harm) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report toxic effect of benzene, intentional self-harm, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T52.1X2A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for toxic effect of benzene, intentional self-harm, such as an emergency visit or first evaluation.

What MS-DRG does T52.1X2A group to?

When toxic effect of benzene, intentional self-harm, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 917, 918, with relative weights from 0.8571 to 1.5684 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of T52.1X2A?

Under the General Equivalence Mappings, toxic effect of benzene, intentional self-harm, initial encounter converts to ICD-9-CM 982.0 (toxic effect benzene) and E950.9 (poison-solid/liquid NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.