2026 ICD-10-CM Diagnosis Code S25.21XSMinor laceration of superior vena cava, sequela
S25.21XS is a billable ICD-10-CM diagnosis code for minor laceration of superior vena cava, sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 299 through 301. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Injury, sequela.
Code Identity
Code Classification
Present on Admission (POA)Billing
S25.21XS is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.
Coding GuidelinesGuidance
The appropriate 7th character is to be added to each code from block Injury of blood vessels of thorax (S25). Use the following options for the applicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Wounds and Injuries
An injury is damage to your body. It is a general term that refers to harm caused by accidents, falls, hits, weapons, and more. In the U.S., millions of people injure themselves every year. These injuries range from minor to life-threatening.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert S25.21XS to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About S25.21XSOverview
Is S25.21XS (Minor laceration of superior vena cava) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report minor laceration of superior vena cava, sequela on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What does the 7th character S in S25.21XS mean?
The final character S makes this a sequela code: it reports a lingering problem that remains after the minor laceration of superior vena cava itself has resolved, not the original event.
What MS-DRG does S25.21XS group to?
When minor laceration of superior vena cava, sequela is the principal diagnosis on an inpatient stay, it groups to MS-DRG 299, 300, 301, with relative weights from 0.7197 to 1.6327 depending on complications. Higher weights mean higher Medicare reimbursement.
Is S25.21XS exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for minor laceration of superior vena cava, sequela on inpatient claims.
What is the ICD-9 equivalent of S25.21XS?
Under the General Equivalence Mappings, minor laceration of superior vena cava, sequela converts to ICD-9-CM 908.4 (lt eff inj thor/abd vess). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
