2026 ICD-10-CM Diagnosis Code R97.8Other abnormal tumor markers

ICD-10-CM Codes›R00–R99›R97›R97

ICD-10-CM R97.8
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

R97.8 is a billable ICD-10-CM diagnosis code for other abnormal tumor markers. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 947 through 948. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. Coders also document this condition as cancer antigen 125 above reference range. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Abnormal findings without diagnosis.

Code Identity

ICD-10-CM Code
R97.8
Billable Status
Yes — Valid for Submission
Code Describes
Other abnormal tumor markers
Short Description
Other abnormal tumor markers
Same as the full description in the CMS dataset.
Parent Code
R97
Abnormal tumor markers

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR97Abnormal tumor markers
CategoryR97Abnormal tumor markers
This CodeR97.8Other abnormal tumor markers

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Cancer antigen 125 above reference range
  • Cancer antigen 19-9 above reference range
  • Endometrial cancer genetic marker of susceptibility positive
  • High tumor mutational burden
  • Ovarian cancer genetic marker of susceptibility positive
  • Prostate specific antigen outside reference range
  • Tumor mutational burden

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Abnormal, abnormality, abnormalities
      • tumor marker NEC
    • Elevated, elevation
      • tumor associated antigens [TAA] NEC
    • Elevated, elevation
      • tumor specific antigens [TSA] NEC

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM017
Abnormal findings without diagnosis
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Laboratory Tests

Laboratory tests check a sample of your blood, urine, or body tissues. A technician or your doctor analyzes the test samples to see if your results fall within the normal range. The tests use a range because what is normal differs from person to person. Many factors affect test results. These include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert R97.8 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
795.89 Abnorml tumor marker NEC
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About R97.8Overview

Is R97.8 (Abnormal tumor markers) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other abnormal tumor markers on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does R97.8 group to?

When other abnormal tumor markers is the principal diagnosis on an inpatient stay, it groups to MS-DRG 947, 948, with relative weights from 0.8005 to 1.2694 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R97.8 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the other abnormal tumor markers is established, that condition takes the principal position instead.

What is the ICD-9 equivalent of R97.8?

Under the General Equivalence Mappings, other abnormal tumor markers converts to ICD-9-CM 795.89 (abnorml tumor marker NEC). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.