2026 ICD-10-CM Diagnosis Code R80.0Isolated proteinuria
ICD-10-CM Codes›R00–R99›R80-R82›R80
- Billable — Valid for Submission
- Not Chronic
R80.0 is a billable ICD-10-CM diagnosis code for isolated proteinuria. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 695 through 696. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Proteinuria.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Isolated proteinuria
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Idiopathic proteinuria
Type 1 Excludes
- isolated proteinuria with specific morphological lesion N06
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- Proteinuria - R80.9
- idiopathic - R80.0
- isolated - R80.0
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Proteinuria
- idiopathic
- Proteinuria
- isolated
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Pre-Eclampsia
a complication of pregnancy, characterized by a complex of symptoms including maternal hypertension and proteinuria with or without pathological edema. symptoms may range between mild and severe. pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.Proteinuria
the presence of proteins in the urine, an indicator of kidney diseases.Kidney Diseases
pathological processes of the kidney or its component tissues.Overflow Proteinuria|Overflow proteinuria
a pathologic condition that occurs when the plasma concentration of low-molecular weight proteins exceeds the tubular capacity to reabsorb the filtered proteins.Grade 1 Proteinuria, CTCAE|Grade 1 Proteinuria|Grade 1 Proteinuria
1+ proteinuria; urinary protein > or = to uln-<1.0 g/24 hrsGrade 2 Proteinuria, CTCAE|Grade 2 Proteinuria|Grade 2 Proteinuria
adult: 2+ and 3+ proteinuria; urinary protein 1.0-<3.5 g/24 hrs; pediatric: urine p/c (protein/creatinine) ratio 0.5-1.9Grade 3 Proteinuria, CTCAE|Grade 3 Proteinuria|Grade 3 Proteinuria
adult: urinary protein >=3.5 g/24 hrs; 4+ proteinuria; pediatric: urine p/c (protein/creatinine) ratio >1.9Maternal Proteinuria
the presence of excessive protein, chiefly albumin but also globulin, in the urine of a pregnant woman.Nephrotic Range Proteinuria
in children, urine protein greater than or equal to 40mg/m^2/h; alternatively, greater than or equal to 0.25gm/mmol creatinine or 2gm/gm creatinine obtained from a first morning specimen.Proteinuria
the presence of abnormal amounts of protein in the urine.Proteinuria, CTCAE 5.0|Proteinuria|Proteinuria
a disorder characterized by laboratory test results that indicate the presence of excessive protein in the urine. it is predominantly albumin, but also globulin.
Patient EducationClinical
Urine and Urination
Your kidneys make urine by filtering wastes and extra water from your blood. The waste is called urea. Your blood carries it to the kidneys. From the kidneys, urine travels down two thin tubes called ureters to the bladder. The bladder stores urine until you are ready to urinate.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert R80.0 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About R80.0Overview
Is R80.0 (Proteinuria) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report isolated proteinuria on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does R80.0 group to?
When isolated proteinuria is the principal diagnosis on an inpatient stay, it groups to MS-DRG 695, 696, with relative weights from 0.6890 to 1.1438 depending on complications. Higher weights mean higher Medicare reimbursement.
Can R80.0 be a principal diagnosis?
Use it with care. This is a symptom code, so once a definitive diagnosis explaining the isolated proteinuria is established, that condition takes the principal position instead.
What is the ICD-9 equivalent of R80.0?
Under the General Equivalence Mappings, isolated proteinuria converts to ICD-9-CM 791.0 (proteinuria). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
