2027 ICD-10-CM Diagnosis Code R11.15Cyclical vomiting syndrome unrelated to migraine

ICD-10-CM Codes›R00–R99›R10-R19›R11

ICD-10-CM R11.15
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

R11.15 is a billable ICD-10-CM diagnosis code for cyclical vomiting syndrome unrelated to migraine. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 393 through 395. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. Coders also document this condition as persistent vomiting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Nausea and vomiting.

Code Identity

ICD-10-CM Code
R11.15
Billable Status
Yes — Valid for Submission
Code Describes
Cyclical vomiting syndrome unrelated to migraine
Short Description
Cyclical vomiting syndrome unrelated to migraine
Same as the full description in the CMS dataset.
Parent Code
R11.1
Vomiting

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR10-R19Symptoms and signs involving the digestive system and abdomen
CategoryR11Nausea and vomiting
This CodeR11.15Cyclical vomiting syndrome unrelated to migraine

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Persistent vomiting
  • Uncontrollable vomiting

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to R11.15: its own notes plus those printed at R11, block R10-R19, and Chapter 18. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Cyclic vomiting syndrome NOS
  • Persistent vomiting

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

On R11.15 itself
  • cyclical vomiting in migraine (G43.A-)
From R11 Nausea and vomiting applies to 9 codes
  • cyclical vomiting associated with migraine (G43.A-)
  • excessive vomiting in pregnancy (O21.-)
  • hematemesis (K92.0)
  • neonatal hematemesis (P54.0)
  • newborn vomiting (P92.0-)
  • psychogenic vomiting (F50.89)
  • vomiting associated with bulimia nervosa (F50.2-)
  • vomiting following gastrointestinal surgery (K91.0)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

On R11.15 itself
  • bulimia nervosa (F50.20)
  • diabetes mellitus due to underlying condition (E08.-)
From Block R10-R19 Symptoms and signs involving the digestive system and abdomen applies to 99 codes
  • congenital or infantile pylorospasm (Q40.0)
  • gastrointestinal hemorrhage (K92.0-K92.2)
  • intestinal obstruction (K56.-)
  • newborn gastrointestinal hemorrhage (P54.0-P54.3)
  • newborn intestinal obstruction (P76.-)
  • pylorospasm (K31.3)
  • signs and symptoms involving the urinary system (R30-R39)
  • symptoms referable to female genital organs (N94.-)
  • symptoms referable to male genital organs (N48-N50)
From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)

Notes

General instructions on how these codes are used.

From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
  • Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
  • The conditions and signs or symptoms included in categories R00-R94 consist of:
  • (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
  • (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
  • (c) provisional diagnosis in a patient who failed to return for further investigation or care;
  • (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
  • (e) cases in which a more precise diagnosis was not available for any other reason;
  • (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name R11.15, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming R11.15: they are not reported together with it, unless the two conditions are unrelated.

  • G43.A Cyclical vomiting
    cyclical vomiting syndrome unrelated to migraine (R11.15)
  • P92.0 Vomiting of newborn
    vomiting of child over 28 days old (R11.-) names R11.-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SYM004
Nausea and vomiting
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Vomiting

    the forcible expulsion of the contents of the stomach through the mouth.

Patient EducationClinical

Nausea and Vomiting

Nausea is when you feel sick to your stomach, as if you are going to throw up. Vomiting is when you throw up.

The full article covers:

  • What are nausea and vomiting?
  • What causes nausea and vomiting?
  • When do I need to see a health care provider for nausea and vomiting?
  • How is the cause of nausea and vomiting diagnosed?
  • What are the treatments for nausea and vomiting?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement R11.15 replaces the following previously assigned code(s):

  • K31.89 - Other diseases of stomach and duodenum
  • R11 - Nausea and vomiting
  • R11.0 - Nausea
  • R11.1 - Vomiting
  • R11.10 - Vomiting, unspecified
  • R11.11 - Vomiting without nausea
  • R11.12 - Projectile vomiting
  • R11.13 - Vomiting of fecal matter
  • R11.14 - Bilious vomiting
  • R11.15 - Cyclical vomiting syndrome unrelated to migraine
  • R11.16 - Cannabis hyperemesis syndrome
  • R11.2 - Nausea with vomiting, unspecified
FY 2020AddedAdded to the ICD-10-CM code setEffective October 1, 2019.
FY 2021–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About R11.15Overview

What is the ICD-10 code for cyclical vomiting syndrome unrelated to migraine?

The ICD-10-CM code for cyclical vomiting syndrome unrelated to migraine is R11.15 (sometimes written as R1115). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is R11.15 (Vomiting) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report cyclical vomiting syndrome unrelated to migraine on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does R11.15 group to?

When cyclical vomiting syndrome unrelated to migraine is the principal diagnosis on an inpatient stay, it groups to MS-DRG 394, 395, 393, with relative weights from 0.6379 to 1.5877 depending on complications. Higher weights mean higher Medicare reimbursement.

Can R11.15 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the cyclical vomiting syndrome unrelated to migraine is established, that condition takes the principal position instead.

Can R11.15 be reported with a code from G43.A?

Not as a rule. The Excludes1 note on R11.15 lists "cyclical vomiting in migraine (G43.A-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).