Hepatomegaly and splenomegaly, not elsewhere classified (R16)

• ICD-10 Index

  • Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00–R99)

    • Symptoms and signs involving the digestive system and abdomen (R10-R19)

      • Hepatomegaly and splenomegaly, not elsewhere classified (R16)

        • R16 - Hepatomegaly and splenomegaly, not elsewhere classified NON-BILLABLE CODE
        • R16.0 - Hepatomegaly, not elsewhere classified BILLABLE CODE
        • R16.1 - Splenomegaly, not elsewhere classified BILLABLE CODE
        • R16.2 - Hepatomegaly with splenomegaly, not elsewhere classified BILLABLE CODE

Clinical Information for Hepatomegaly and splenomegaly, not elsewhere classified (R16)

Gaucher Disease - An autosomal recessive disorder caused by a deficiency of acid beta-glucosidase (GLUCOSYLCERAMIDASE) leading to intralysosomal accumulation of glycosylceramide mainly in cells of the MONONUCLEAR PHAGOCYTE SYSTEM. The characteristic Gaucher cells, glycosphingolipid-filled HISTIOCYTES, displace normal cells in BONE MARROW and visceral organs causing skeletal deterioration, hepatosplenomegaly, and organ dysfunction. There are several subtypes based on the presence and severity of neurological involvement.

Splenomegaly - Enlargement of the spleen.