2026 ICD-10-CM Diagnosis Code M89.59Osteolysis, multiple sites

ICD-10-CM Codes›M00–M99›M86-M90›M89

ICD-10-CM M89.59
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

M89.59 is a billable ICD-10-CM diagnosis code for osteolysis, multiple sites. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 564 through 566. Coders also document this condition as abnormally short fourth metacarpal. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified bone disease and musculoskeletal deformities.

Code Identity

ICD-10-CM Code
M89.59
Billable Status
Yes — Valid for Submission
Code Describes
Osteolysis, multiple sites
Short Description
Osteolysis, multiple sites
Same as the full description in the CMS dataset.
Parent Code
M89.5
Osteolysis

Code Classification

ChapterM00–M99Diseases of the musculoskeletal system and connective tissue
SectionM86-M90Other osteopathies
CategoryM89Other disorders of bone
This CodeM89.59Osteolysis, multiple sites

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Abnormally short fourth metacarpal
  • Deformity of metacarpal
  • Idiopathic multicentric osteolysis
  • Idiopathic osteolyses
  • Longitudinal deficiency of metacarpal bone
  • Talo-patello-scaphoid osteolysis syndrome

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Osteolysis
      • multiple sites

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MUS028
Other specified bone disease and musculoskeletal deformities
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hajdu-Cheney Syndrome

    rare, autosomal dominant syndrome characterized by acro-osteolysis, generalized osteoporosis, and skull deformations.

  • Osteolysis

    dissolution of bone that particularly involves the removal or loss of calcium.

  • Osteolysis, Essential

    syndromes of bone destruction where the cause is not obvious such as neoplasia, infection, or trauma. the destruction follows various patterns: massive (gorham disease), multicentric (hajdu-cheney syndrome), or carpal/tarsal.

  • Gorham-Stout Disease|Disappearing Bone Disease|Essential Osteolysis|GDS|Gorham disease|Idiopathic Massive Osteolysis|Massive Gorham Osteolysis|Massive Osteolysis|Morbus Gorham-Stout Disease|Phantom Bone Disease|Progressive Massive Osteolysis|Vanishing Bone Disease

    a rare bone disorder characterized by progressive bone loss due to abnormal lymphatic vessel proliferation resorption of bone.

  • Regional Migratory Osteoporosis|Migratory Osteolysis|Migratory osteolysis

    a rare arthralgia affecting the weight-bearing joints of the lower limb that is characterized by bone marrow edema with subchondral sparing without subchondral fracture.

  • Acroosteolysis

    a condition that is characterized by degeneration of the distal phalanges.

  • Inherited Osteolysis Syndrome

    a genetically heterogenous group of disorders characterized by loss of bone tissue.

  • Multicentric Carpotarsal Osteolysis Syndrome|MCTO

    an autosomal dominant condition caused by mutation(s) in the mafb gene, encoding transcription factor mafb. it is characterized by progressive destruction of the carpal and tarsal bones, usually with onset in early childhood.

  • Multicentric Osteolysis, Nodulosis, and Arthropathy|Hereditary Multicentric Osteolysis|MONA

    a rare, autosomal recessive inherited syndrome caused by mutations in the mmp2 gene. it is characterized by the presence of multiple, painless subcutaneous nodules, osteolysis particularly in the hands and feet, osteoporosis, and arthropathy.

  • Osteolysis

    dissolution of bone; applied especially to the removal or loss of the calcium of bone.

Patient EducationClinical

Bone Diseases

Your bones help you move, give you shape and support your body. They are living tissues that rebuild constantly throughout your life. During childhood and your teens, your body adds new bone faster than it removes old bone. After about age 20, you can lose bone faster than you make bone.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert M89.59 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
733.99 Bone & cartilage dis NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About M89.59Overview

Is M89.59 (Osteolysis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report osteolysis, multiple sites on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does M89.59 group to?

When osteolysis, multiple sites is the principal diagnosis on an inpatient stay, it groups to MS-DRG 564, 565, 566, with relative weights from 0.7493 to 1.5436 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of M89.59?

Under the General Equivalence Mappings, osteolysis, multiple sites converts to ICD-9-CM 733.99 (bone & cartilage dis NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.