2026 ICD-10-CM Diagnosis Code M89.50Osteolysis, unspecified site
ICD-10-CM Codes›M00–M99›M86-M90›M89
- Billable — Valid for Submission
- Not Chronic
M89.50 is a billable ICD-10-CM diagnosis code for osteolysis, unspecified site. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 564 through 566. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified bone disease and musculoskeletal deformities.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Acroosteolysis
- Acroosteolysis, keloid-like lesions, premature aging syndrome
- Autosomal recessive distal osteolysis syndrome
- Congenital hypotrichia
- Familial expansile osteolysis
- Hereditary acroosteolysis
- Hypotrichosis, osteolysis, periodontitis, palmoplantar keratoderma syndrome
- Idiopathic osteolyses
- Migratory osteolysis
- Multicentric osteolysis nodulosis arthropathy spectrum
- Osteolysis
- Osteolysis due to and following traumatic injury
- Osteolysis following surgical procedure on skeletal system
- Secondary osteolysis
- Torg type osteolysis
- Winchester syndrome
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- Osteolysis - M89.50
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Osteolysis
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Hajdu-Cheney Syndrome
rare, autosomal dominant syndrome characterized by acro-osteolysis, generalized osteoporosis, and skull deformations.Osteolysis
dissolution of bone that particularly involves the removal or loss of calcium.Osteolysis, Essential
syndromes of bone destruction where the cause is not obvious such as neoplasia, infection, or trauma. the destruction follows various patterns: massive (gorham disease), multicentric (hajdu-cheney syndrome), or carpal/tarsal.Gorham-Stout Disease|Disappearing Bone Disease|Essential Osteolysis|GDS|Gorham disease|Idiopathic Massive Osteolysis|Massive Gorham Osteolysis|Massive Osteolysis|Morbus Gorham-Stout Disease|Phantom Bone Disease|Progressive Massive Osteolysis|Vanishing Bone Disease
a rare bone disorder characterized by progressive bone loss due to abnormal lymphatic vessel proliferation resorption of bone.Regional Migratory Osteoporosis|Migratory Osteolysis|Migratory osteolysis
a rare arthralgia affecting the weight-bearing joints of the lower limb that is characterized by bone marrow edema with subchondral sparing without subchondral fracture.Acroosteolysis
a condition that is characterized by degeneration of the distal phalanges.Inherited Osteolysis Syndrome
a genetically heterogenous group of disorders characterized by loss of bone tissue.Multicentric Carpotarsal Osteolysis Syndrome|MCTO
an autosomal dominant condition caused by mutation(s) in the mafb gene, encoding transcription factor mafb. it is characterized by progressive destruction of the carpal and tarsal bones, usually with onset in early childhood.Multicentric Osteolysis, Nodulosis, and Arthropathy|Hereditary Multicentric Osteolysis|MONA
a rare, autosomal recessive inherited syndrome caused by mutations in the mmp2 gene. it is characterized by the presence of multiple, painless subcutaneous nodules, osteolysis particularly in the hands and feet, osteoporosis, and arthropathy.Osteolysis
dissolution of bone; applied especially to the removal or loss of the calcium of bone.
Patient EducationClinical
Bone Diseases
Your bones help you move, give you shape and support your body. They are living tissues that rebuild constantly throughout your life. During childhood and your teens, your body adds new bone faster than it removes old bone. After about age 20, you can lose bone faster than you make bone.
Read the full article at MedlinePlus
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Convert M89.50 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About M89.50Overview
Is M89.50 (Osteolysis) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report osteolysis, unspecified site on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does M89.50 group to?
When osteolysis, unspecified site is the principal diagnosis on an inpatient stay, it groups to MS-DRG 564, 565, 566, with relative weights from 0.7493 to 1.5436 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of M89.50?
Under the General Equivalence Mappings, osteolysis, unspecified site converts to ICD-9-CM 733.99 (bone & cartilage dis NEC). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
