2026 ICD-10-CM Diagnosis Code E74.31Sucrase-isomaltase deficiency
ICD-10-CM Codes›E00–E89›E70-E88›E74
- Billable — Valid for Submission
- Chronic Condition
E74.31 is a billable ICD-10-CM diagnosis code for sucrase-isomaltase deficiency. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 391 through 392. Coders also document this condition as deficiency of isomaltase. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.
E74.31 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model. It still risk-adjusts in the RxHCC Part D (V08) category 42 for payment year 2026.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
E74.31 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model, but it maps to payment categories in the other CMS models shown below.
Source: CMS Payment Year 2026 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Deficiency of isomaltase
- Disaccharidase deficiency
- Intestinal disaccharidase deficiency
- Sucrase-isomaltase deficiency
- Sucrose intolerance due to sucrase-isomaltase deficiency
Index to Diseases and InjuriesGuidance
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Carbohydrate Metabolism Disorders
Metabolism is the process your body uses to make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system (enzymes) break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert E74.31 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About E74.31Overview
What is the ICD-10 code for sucrase-isomaltase deficiency?
The ICD-10-CM code for sucrase-isomaltase deficiency is E74.31 (sometimes written as E7431). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
Is E74.31 (Other disorders of intestinal carbohydrate absorption) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report sucrase-isomaltase deficiency on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does E74.31 group to?
When sucrase-isomaltase deficiency is the principal diagnosis on an inpatient stay, it groups to MS-DRG 391, 392, with relative weights from 0.7796 to 1.2683 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of E74.31?
Under the General Equivalence Mappings, sucrase-isomaltase deficiency converts to ICD-9-CM 271.3 (disaccharidase def/malab). The mapping is approximate, so confirm the match fits the documentation.
Does E74.31 risk-adjust for Medicare Advantage payment?
Not for Medicare Advantage: E74.31 maps to no category in the CMS-HCC V28 model. It still risk-adjusts in the RxHCC Part D (V08) category 42 (Acromegaly and Other Endocrine and Metabolic Disorders).
