2026 ICD-10-CM Diagnosis Code D57.20Sickle-cell/Hb-C disease without crisis
ICD-10-CM Codes›D50–D89›D55-D59›D57
- Billable — Valid for Submission
- Risk Adjusts — HCC 108
- Chronic Condition
D57.20 is a billable ICD-10-CM diagnosis code for Sickle-cell/Hb-C disease without crisis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 811 through 812. Coders also document this condition as hemoglobin S sickling disorder without crisis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Sickle cell trait/anemia.
For Medicare Advantage risk adjustment, D57.20 maps to CMS-HCC Category 108 (Sickle Cell Disorders, Except Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero; Beta Thalassemia Major) under the V28 model, adding a risk factor of about 0.146 for a community, non-dual, aged beneficiary in payment year 2026.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
D57.20 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2026.
Source: CMS Payment Year 2026 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Hemoglobin S sickling disorder without crisis
- Mixed hemoglobin disorder
- Sickle cell retinopathy
- Sickle cell-hemoglobin C disease
- Sickle cell-hemoglobin C disease without crisis
- Sickle cell-hemoglobin C retinopathy
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Disease, diseased See Also: Syndrome;
Hb-C D57.20
without crisis D57.20
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Sickle Cell Disease
Sickle cell disease (SCD) is a group of inherited red blood cell disorders. If you have SCD, there is a problem with your hemoglobin. Hemoglobin is a protein in red blood cells that carries oxygen throughout the body. With SCD, the hemoglobin forms into stiff rods within the red blood cells. This changes the shape of the red blood cells.
The full article covers:
- What is sickle cell disease (SCD)?
- What causes sickle cell disease (SCD)?
- Who is more likely to have sickle cell disease (SCD)?
- What are the symptoms of sickle cell disease (SCD)?
- How is sickle cell disease (SCD) diagnosed?
- What are the treatments for sickle cell disease (SCD)?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert D57.20 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About D57.20Overview
What is the ICD-10 code for Sickle-cell/Hb-C disease without crisis?
The ICD-10-CM code for Sickle-cell/Hb-C disease without crisis is D57.20 (sometimes written as D5720). It is billable on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
Is D57.20 (Sickle-cell/Hb-C disease) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report Sickle-cell/Hb-C disease without crisis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does D57.20 group to?
When Sickle-cell/Hb-C disease without crisis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 811, 812, with relative weights from 0.9182 to 1.4043 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of D57.20?
Under the General Equivalence Mappings, Sickle-cell/Hb-C disease without crisis converts to ICD-9-CM 282.63 (Hb-SS/hb-C dis w/o crsis). The mapping is a direct match.
What HCC is D57.20?
D57.20 (Sickle-cell/Hb-C disease without crisis) maps to CMS-HCC Category 108 (Sickle Cell Disorders, Except Sickle Cell Anemia (Hb-SS) and Thalassemia Beta Zero; Beta Thalassemia Major), commonly written as HCC 108, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2026. It mapped to HCC 46 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. It does not map to any RxHCC in the Part D prescription drug model.
Does D57.20 risk-adjust for Medicare Advantage payment?
Yes. When documented and reported on a Medicare Advantage encounter, D57.20 adds a risk adjustment factor of about 0.146 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.098 to 0.416 depending on the payment segment). A more severe related category (HCC 107) supersedes it when both are reported. See the full factor table on the HCC 108 category page.
