2026 ICD-10-CM Diagnosis Code C80.2Malignant neoplasm associated with transplanted organ

ICD-10-CM Codes›C00–D49›C76-C80›C80

ICD-10-CM C80.2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C80.2 is a billable ICD-10-CM diagnosis code for malignant neoplasm associated with transplanted organ. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 826 through 830, 843 through 845. The code is not accepted as a principal diagnosis by the Medicare Code Editor. Coders also document this condition as donor derived melanoma. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Malignant neoplasm, unspecified.

Code Identity

ICD-10-CM Code
C80.2
Billable Status
Yes — Valid for Submission
Code Describes
Malignant neoplasm associated with transplanted organ
Short Description
Malignant neoplasm associated with transplanted organ
Same as the full description in the CMS dataset.
Parent Code
C80
Malignant neoplasm without specification of site

Code Classification

ChapterC00–D49Neoplasms
SectionC76-C80Malignant neoplasms of ill-defined, other secondary and unspecified sites
CategoryC80Malignant neoplasm without specification of site
This CodeC80.2Malignant neoplasm associated with transplanted organ

Code EditsBilling

Medicare Code Editor checks that affect claim validity for C80.2.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Donor derived melanoma
  • Neoplasm following transplantation of kidney
  • Post-transplant neoplasia

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Code First

  • complication of transplanted organ T86

Use Additional Code

  • code to identify the specific malignancy

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Complication(s) (from) (of)
      • transplant
        • malignant neoplasm

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO071
Malignant neoplasm, unspecified
Default principal diagnosis: inpatient No · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary		Malig.
Secondary		Ca
in situ		BenignUncertainUnspec.
associated with transplanted organC80.2–––––

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Convert C80.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
199.2 Malig neopl-transp organ
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C80.2Overview

Is C80.2 (Malignant neoplasm without specification of site) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm associated with transplanted organ on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C80.2 group to?

On inpatient claims, malignant neoplasm associated with transplanted organ maps to MS-DRG 826, 827, 828, 829, 830, 843, 844, 845, with relative weights from 0.8516 to 4.6778 depending on complications. Higher weights mean higher Medicare reimbursement.

Can C80.2 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because malignant neoplasm associated with transplanted organ describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

What is the ICD-9 equivalent of C80.2?

Under the General Equivalence Mappings, malignant neoplasm associated with transplanted organ converts to ICD-9-CM 199.2 (malig neopl-transp organ). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.