2026 ICD-10-CM Diagnosis Code C80.0Disseminated malignant neoplasm, unspecified

ICD-10-CM CodesC00–D49C76-C80C80

ICD-10-CM C80.0
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C80.0 is a billable ICD-10-CM diagnosis code for disseminated malignant neoplasm, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 826 through 830, 843 through 845. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Malignant neoplasm, unspecified.

Code Identity

ICD-10-CM Code
C80.0
Billable Status
Yes — Valid for Submission
Code Describes
Disseminated malignant neoplasm, unspecified
Short Description
Disseminated malignant neoplasm, unspecified
Same as the full description in the CMS dataset.
Parent Code
Malignant neoplasm without specification of site

Code Classification

ChapterC00–D49Neoplasms
SectionC76-C80Malignant neoplasms of ill-defined, other secondary and unspecified sites
CategoryC80Malignant neoplasm without specification of site
This CodeC80.0Disseminated malignant neoplasm, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Adenocarcinoma carcinomatosis
  • Carcinomatosis
  • Chorea due to widespread metastatic malignant neoplastic disease
  • Melanoma carcinomatosis
  • Metastatic small cell neuroendocrine carcinoma
  • Multiple malignancy
  • Small cell carcinoma carcinomatosis
  • Squamous cell carcinomatosis
  • Undifferentiated large cell carcinomatosis
  • Widespread metastatic malignant neoplastic disease

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Carcinomatosis NOS
  • Generalized cancer, unspecified site (primary) (secondary)
  • Generalized malignancy, unspecified site (primary) (secondary)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Carcinoma(malignant)
      • generalized, with unspecified primary site
    • Carcinomatosis
    • Carcinomatosis
      • unspecified site (primary) (secondary)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO071
Malignant neoplasm, unspecified
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
disease, generalizedC80.0
disseminatedC80.0
generalizedC80.0

Patient EducationClinical

Cancer

Cancer is not just one disease but many diseases. Cancer begins in your cells, which are the building blocks of your body. Usually, your body forms new cells as needed, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should.

The full article covers:

  • What is cancer?
  • What are the types of cancer?
  • How does cancer develop?
  • What are the symptoms of cancer?
  • How is cancer diagnosed?
  • What are the treatments for cancer?
  • Can cancer be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert C80.0 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
199.0 Malig neo disseminated
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C80.0Overview

Is C80.0 (Malignant neoplasm without specification of site) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report disseminated malignant neoplasm, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C80.0 group to?

When disseminated malignant neoplasm, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 826, 827, 828, 829, 830, 843, 844, 845, with relative weights from 0.8516 to 4.6778 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of C80.0?

Under the General Equivalence Mappings, disseminated malignant neoplasm, unspecified converts to ICD-9-CM 199.0 (malig neo disseminated). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.