2027 ICD-10-CM Diagnosis Code C79.51Secondary malignant neoplasm of bone
ICD-10-CM Codes›C00–D49›C76-C80›C79
- Billable — Valid for Submission
- CC — Complication or Comorbidity
- Risk Adjusts — HCC 18
- Chronic Condition
C79.51 is a billable ICD-10-CM diagnosis code for secondary malignant neoplasm of bone. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 456 through 458, 542 through 544. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 22 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Secondary malignancies.
For Medicare Advantage risk adjustment, C79.51 maps to CMS-HCC Category 18 (Cancer Metastatic to Bone, Other and Unspecified Metastatic Cancer; Acute Leukemia Except Myeloid) under the V28 model, adding a risk factor of about 2.341 for a community, non-dual, aged beneficiary in payment year 2027.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
C79.51 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.
Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Malignant neoplasm of bone, connective tissue, skin and breast
- Malignant neoplasm of calcaneum
- Malignant neoplasm of carpal bone - hamate
- Malignant neoplasm of carpal bone - lunate
- Malignant neoplasm of carpal bone - pisiform
- Malignant neoplasm of carpal bone - scaphoid
- Malignant neoplasm of carpal bone - trapezium
- Malignant neoplasm of carpal bone - trapezoid
- Malignant neoplasm of intermediate cuneiform
- Malignant neoplasm of lateral cuneiform
- Malignant neoplasm of long bone of lower leg
- Malignant neoplasm of malar bone
- Malignant neoplasm of medial cuneiform
- Malignant neoplasm of metacarpal bones
- Malignant neoplasm of metatarsal bone of foot
- Malignant neoplasm of nasal septum
- Malignant neoplasm of nasal skeleton
- Malignant neoplasm of navicular bone of foot
- Malignant neoplasm of phalanges of foot
- Malignant neoplasm of phalanges of hand
- Malignant neoplasm of thoracic vertebral column
- Malignant neoplasm of vertebra
- Mass of parietal bone of skull
- Metastatic adenocarcinoma to bone
- Metastatic carcinoma to bone of clavicle
- Metastatic carcinoma to bone of lower limb
- Metastatic carcinoma to bone of rib
- Metastatic carcinoma to bone of sternum
- Metastatic carcinoma to bone of upper limb
- Metastatic carcinoma to bone, connective tissue, skin and breast
- Metastatic carcinoma to breast
- Metastatic carcinoma to pelvic bones, sacrum and coccyx
- Metastatic carcinoma to scapula
- Metastatic malignant neoplasm to acromion
- Metastatic malignant neoplasm to articular cartilage
- Metastatic malignant neoplasm to bone
- Metastatic malignant neoplasm to bone of face
- Metastatic malignant neoplasm to bone of lower limb
- Metastatic malignant neoplasm to bone of skull
- Metastatic malignant neoplasm to bone of upper limb
- Metastatic malignant neoplasm to calcaneus
- Metastatic malignant neoplasm to carpal bone
- Metastatic malignant neoplasm to cervical vertebral column
- Metastatic malignant neoplasm to cheek
- Metastatic malignant neoplasm to clavicle
- Metastatic malignant neoplasm to coccyx
- Metastatic malignant neoplasm to cuboid
- Metastatic malignant neoplasm to ethmoid bone
- Metastatic malignant neoplasm to femur
- Metastatic malignant neoplasm to fibula
- Metastatic malignant neoplasm to first cuneiform bone of foot
- Metastatic malignant neoplasm to forearm
- Metastatic malignant neoplasm to frontal bone
- Metastatic malignant neoplasm to hamate bone
- Metastatic malignant neoplasm to hand
- Metastatic malignant neoplasm to ilium
- Metastatic malignant neoplasm to ischium
- Metastatic malignant neoplasm to long bone of lower limb
- Metastatic malignant neoplasm to long bone of upper limb
- Metastatic malignant neoplasm to lower leg
- Metastatic malignant neoplasm to lumbar vertebral column
- Metastatic malignant neoplasm to lunate bone
- Metastatic malignant neoplasm to mandible
- Metastatic malignant neoplasm to maxilla
- Metastatic malignant neoplasm to metacarpal bone
- Metastatic malignant neoplasm to metatarsal bone
- Metastatic malignant neoplasm to nasal bone
- Metastatic malignant neoplasm to navicular bone of foot
- Metastatic malignant neoplasm to nose
- Metastatic malignant neoplasm to occipital bone
- Metastatic malignant neoplasm to palatine bone
- Metastatic malignant neoplasm to parietal bone
- Metastatic malignant neoplasm to patella
- Metastatic malignant neoplasm to pelvic bone
- Metastatic malignant neoplasm to phalanx of foot
- Metastatic malignant neoplasm to phalanx of hand
- Metastatic malignant neoplasm to pisiform bone of wrist region
- Metastatic malignant neoplasm to pubis
- Metastatic malignant neoplasm to radius
- Metastatic malignant neoplasm to rib
- Metastatic malignant neoplasm to sacrococcygeal region
- Metastatic malignant neoplasm to sacrum
- Metastatic malignant neoplasm to scaphoid bone
- Metastatic malignant neoplasm to scapula
- Metastatic malignant neoplasm to second cuneiform bone of foot
- Metastatic malignant neoplasm to septum of nose
- Metastatic malignant neoplasm to short bone of lower limb
- Metastatic malignant neoplasm to short bone of upper limb
- Metastatic malignant neoplasm to sphenoid bone
- Metastatic malignant neoplasm to sternum
- Metastatic malignant neoplasm to talus
- Metastatic malignant neoplasm to tarsal bone
- Metastatic malignant neoplasm to temporal bone
- Metastatic malignant neoplasm to thigh
- Metastatic malignant neoplasm to third cuneiform bone of foot
- Metastatic malignant neoplasm to thoracic vertebral column
- Metastatic malignant neoplasm to tibia
- Metastatic malignant neoplasm to trapezium
- Metastatic malignant neoplasm to trapezoid bone
- Metastatic malignant neoplasm to ulna
- Metastatic malignant neoplasm to vertebral column
- Metastatic malignant neoplasm to vomer
- Metastatic malignant neoplasm to zygomatic bone
- Metastatic nuclear protein in testis associated carcinoma to bone
- Metastatic osteosarcoma to articular cartilage of clavicle
- Metastatic osteosarcoma to articular cartilage of rib
- Metastatic osteosarcoma to articular cartilage of sternum
- Metastatic osteosarcoma to articular cartilage of vertebra
- Metastatic osteosarcoma to bone
- Metastatic osteosarcoma to bone of clavicle
- Metastatic osteosarcoma to bone of head
- Metastatic osteosarcoma to bone of rib
- Metastatic osteosarcoma to bone of sternum
- Metastatic osteosarcoma to bone of vertebra
- Metastatic squamous cell carcinoma to bone
- Neoplasm of acromion
- Neoplasm of calcaneus
- Neoplasm of coccyx
- Neoplasm of cuboid
- Neoplasm of ethmoid bone
- Neoplasm of first cuneiform bone of foot
- Neoplasm of frontal bone
- Neoplasm of hamate bone
- Neoplasm of ilium
- Neoplasm of ischium
- Neoplasm of lunate bone
- Neoplasm of metacarpal bone
- Neoplasm of metatarsal bone
- Neoplasm of nasal bone
- Neoplasm of navicular bone of foot
- Neoplasm of occipital bone
- Neoplasm of palatine bone
- Neoplasm of parietal bone
- Neoplasm of patella
- Neoplasm of phalanx of foot
- Neoplasm of phalanx of hand
- Neoplasm of pisiform bone of wrist region
- Neoplasm of pubis
- Neoplasm of scaphoid bone
- Neoplasm of second cuneiform bone of foot
- Neoplasm of sphenoid bone
- Neoplasm of talus
- Neoplasm of third cuneiform bone of foot
- Neoplasm of trapezium
- Neoplasm of trapezoid bone
- Neoplasm of vomer
- Neoplasm of zygomatic bone
- NUT carcinoma
- Osteosarcoma of articular cartilage of clavicle
- Osteosarcoma of articular cartilage of rib
- Osteosarcoma of articular cartilage of sternum
- Osteosarcoma of articular cartilage of vertebra
- Osteosarcoma of bone of clavicle
- Osteosarcoma of bone of head
- Osteosarcoma of bone of rib
- Osteosarcoma of bone of upper limb
- Osteosarcoma of bone of vertebra
- Osteosarcoma of sternum
- Pathologic fracture of bone at site of metastatic neoplasm
- Pathologic fracture of vertebra at site of metastatic neoplasm
- Pathologic fracture of vertebra at site of neoplasm
- Pathological fracture of vertebra
- Sarcoma of clavicle
- Sarcoma of rib
- Sarcoma of sternum
- Sarcoma of vertebra
- Secondary osteosarcoma following treatment or disease
- Tumor invades bone
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to C79.51: its own notes plus those printed at C79.5, C79, and Chapter 2. A note printed at a category, block or chapter applies to every code under it.
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- secondary carcinoid tumors of bone (C7B.03)
Notes
General instructions on how these codes are used.
- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name C79.51, its category, or a range that includes it.
Applicable To 2
These notes mention C79.51.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Metastatic Malignant Neoplasm to the Bone
a malignant neoplasm that has spread to the bone from another anatomic site.
Table of NeoplasmsClinical
Anatomical sites in the Table of Neoplasms that reference this code family.
| Site | Malig. Primary | Malig. Secondary | Ca in situ | Benign | Uncertain | Unspec. |
|---|---|---|---|---|---|---|
| alveolar › ridge or process | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| alveolar › ridge or process › lower | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| alveolar › ridge or process › upper | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| atlas | C41.2 | C79.51 | – | D16.6 | D48.0 | D49.2 |
| bone (periosteum) | C41.9 | C79.51 | – | D16.9 | D48.0 | D49.2 |
| bone (periosteum) › acetabulum | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › ankle | C40.3 | C79.51 | – | D16.3 | – | – |
| bone (periosteum) › arm NEC | C40.0 | C79.51 | – | D16.0 | – | – |
| bone (periosteum) › astragalus | C40.3 | C79.51 | – | D16.3 | – | – |
| bone (periosteum) › atlas | C41.2 | C79.51 | – | D16.6 | D48.0 | D49.2 |
| bone (periosteum) › axis | C41.2 | C79.51 | – | D16.6 | D48.0 | D49.2 |
| bone (periosteum) › back NEC | C41.2 | C79.51 | – | D16.6 | D48.0 | D49.2 |
| bone (periosteum) › calcaneus | C40.3 | C79.51 | – | D16.3 | – | – |
| bone (periosteum) › calvarium | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › carpus (any) | C40.1 | C79.51 | – | D16.1 | – | – |
| bone (periosteum) › cartilage NEC | C41.9 | C79.51 | – | D16.9 | D48.0 | D49.2 |
| bone (periosteum) › clavicle | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| bone (periosteum) › clivus | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › coccygeal vertebra | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › coccyx | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › costal cartilage | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| bone (periosteum) › costovertebral joint | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| bone (periosteum) › cranial | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › cuboid | C40.3 | C79.51 | – | D16.3 | – | – |
| bone (periosteum) › cuneiform | C41.9 | C79.51 | – | D16.9 | D48.0 | D49.2 |
| bone (periosteum) › elbow | C40.0 | C79.51 | – | D16.0 | – | – |
| bone (periosteum) › ethmoid (labyrinth) | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › face | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › femur (any part) | C40.2 | C79.51 | – | D16.2 | – | – |
| bone (periosteum) › fibula (any part) | C40.2 | C79.51 | – | D16.2 | – | – |
| bone (periosteum) › finger (any) | C40.1 | C79.51 | – | D16.1 | – | – |
| bone (periosteum) › foot | C40.3 | C79.51 | – | D16.3 | – | – |
| bone (periosteum) › forearm | C40.0 | C79.51 | – | D16.0 | – | – |
| bone (periosteum) › frontal | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › hand | C40.1 | C79.51 | – | D16.1 | – | – |
| bone (periosteum) › heel | C40.3 | C79.51 | – | D16.3 | – | – |
| bone (periosteum) › hip | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › humerus (any part) | C40.0 | C79.51 | – | D16.0 | – | – |
| bone (periosteum) › hyoid | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › ilium | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › innominate | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › intervertebral cartilage or disc | C41.2 | C79.51 | – | D16.6 | D48.0 | D49.2 |
| bone (periosteum) › ischium | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › jaw (lower) | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| bone (periosteum) › knee | C40.2 | C79.51 | – | D16.2 | – | – |
| bone (periosteum) › leg NEC | C40.2 | C79.51 | – | D16.2 | – | – |
| bone (periosteum) › limb NEC | C40.9 | C79.51 | – | D16.9 | – | – |
| bone (periosteum) › limb NEC › lower (long bones) | C40.2 | C79.51 | – | D16.2 | – | – |
| bone (periosteum) › limb NEC › lower (long bones) › short bones | C40.3 | C79.51 | – | D16.3 | – | – |
| bone (periosteum) › limb NEC › upper (long bones) | C40.0 | C79.51 | – | D16.0 | – | – |
| bone (periosteum) › limb NEC › upper (long bones) › short bones | C40.1 | C79.51 | – | D16.1 | – | – |
| bone (periosteum) › malar | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › mandible | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| bone (periosteum) › mastoid | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › maxilla, maxillary (superior) | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › maxilla, maxillary (superior) › inferior | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| bone (periosteum) › metacarpus (any) | C40.1 | C79.51 | – | D16.1 | – | – |
| bone (periosteum) › metatarsus (any) | C40.3 | C79.51 | – | D16.3 | – | – |
| bone (periosteum) › navicular › ankle | C40.3 | C79.51 | – | – | – | – |
| bone (periosteum) › navicular › hand | C40.1 | C79.51 | – | – | – | – |
| bone (periosteum) › nose, nasal | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › occipital | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › orbit | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › parietal | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › patella | C40.2 | C79.51 | – | – | – | – |
| bone (periosteum) › pelvic | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › phalanges › foot | C40.3 | C79.51 | – | – | – | – |
| bone (periosteum) › phalanges › hand | C40.1 | C79.51 | – | – | – | – |
| bone (periosteum) › pubic | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › radius (any part) | C40.0 | C79.51 | – | D16.0 | – | – |
| bone (periosteum) › rib | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| bone (periosteum) › sacral vertebra | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › sacrum | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › scaphoid › of ankle | C40.3 | C79.51 | – | – | – | – |
| bone (periosteum) › scaphoid › of hand | C40.1 | C79.51 | – | – | – | – |
| bone (periosteum) › scapula (any part) | C40.0 | C79.51 | – | D16.0 | – | – |
| bone (periosteum) › sella turcica | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › shoulder | C40.0 | C79.51 | – | D16.0 | – | – |
| bone (periosteum) › skull | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › sphenoid | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › spine, spinal (column) | C41.2 | C79.51 | – | D16.6 | D48.0 | D49.2 |
| bone (periosteum) › spine, spinal (column) › coccyx | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › spine, spinal (column) › sacrum | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › sternum | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| bone (periosteum) › tarsus (any) | C40.3 | C79.51 | – | – | – | – |
| bone (periosteum) › temporal | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › thumb | C40.1 | C79.51 | – | – | – | – |
| bone (periosteum) › tibia (any part) | C40.2 | C79.51 | – | – | – | – |
| bone (periosteum) › toe (any) | C40.3 | C79.51 | – | – | – | – |
| bone (periosteum) › trapezium | C40.1 | C79.51 | – | – | – | – |
| bone (periosteum) › trapezoid | C40.1 | C79.51 | – | – | – | – |
| bone (periosteum) › turbinate | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › ulna (any part) | C40.0 | C79.51 | – | D16.0 | – | – |
| bone (periosteum) › unciform | C40.1 | C79.51 | – | – | – | – |
| bone (periosteum) › vertebra (column) | C41.2 | C79.51 | – | D16.6 | D48.0 | D49.2 |
| bone (periosteum) › vertebra (column) › coccyx | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › vertebra (column) › sacrum | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| bone (periosteum) › vomer | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| bone (periosteum) › wrist | C40.1 | C79.51 | – | – | – | – |
| bone (periosteum) › xiphoid process | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| bone (periosteum) › zygomatic | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| calvarium | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| carpus (any bone) | C40.1 | C79.51 | – | D16.1 | – | – |
| cartilage (articular) (joint) NEC [See Also: Neoplasm, bone] | C41.9 | C79.51 | – | D16.9 | D48.0 | D49.2 |
| cartilage (articular) (joint) NEC [See Also: Neoplasm, bone] › costal | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| cartilage (articular) (joint) NEC [See Also: Neoplasm, bone] › ensiform | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| cartilage (articular) (joint) NEC [See Also: Neoplasm, bone] › intervertebral | C41.2 | C79.51 | – | D16.6 | D48.0 | D49.2 |
| cartilage (articular) (joint) NEC [See Also: Neoplasm, bone] › rib | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| cartilage (articular) (joint) NEC [See Also: Neoplasm, bone] › semilunar (knee) | C40.2 | C79.51 | – | D16.2 | D48.0 | D49.2 |
| clavicle | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| clivus | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| coccygeal › vertebra | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| coccyx | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| costal cartilage | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| costovertebral joint | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| disc, intervertebral | C41.2 | C79.51 | – | D16.6 | D48.0 | D49.2 |
| ensiform cartilage | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| ethmoid (sinus) › bone or labyrinth | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| femur (any part) | C40.2 | C79.51 | – | D16.2 | – | – |
| fibula (any part) | C40.2 | C79.51 | – | D16.2 | – | – |
| frontal › bone | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| humerus (any part) | C40.0 | C79.51 | – | D16.0 | – | – |
| ilium | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| intervertebral cartilage or disc | C41.2 | C79.51 | – | D16.6 | D48.0 | D49.2 |
| ischium | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| jaw › bone | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| jaw › bone › lower | C41.1 | C79.51 | – | D16.5 | – | – |
| jaw › bone › upper | C41.0 | C79.51 | – | D16.4 | – | – |
| joint NEC [See Also: Neoplasm, bone] | C41.9 | C79.51 | – | D16.9 | D48.0 | D49.2 |
| joint NEC [See Also: Neoplasm, bone] › acromioclavicular | C40.0 | C79.51 | – | D16.0 | – | – |
| joint NEC [See Also: Neoplasm, bone] › costovertebral | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| joint NEC [See Also: Neoplasm, bone] › sternocostal | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| joint NEC [See Also: Neoplasm, bone] › temporomandibular | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| malar | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| mandible | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| mandible › alveolar › ridge or process | C41.1 | C79.51 | – | D16.5 | D48.0 | D49.2 |
| mastoid (air cells) (antrum) (cavity) › bone or process | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| maxilla, maxillary (superior) | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| maxilla, maxillary (superior) › alveolar › ridge or process (carcinoma) | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| maxilla, maxillary (superior) › carcinoma | C03.0 | C79.51 | – | – | – | – |
| meniscus, knee joint (lateral) (medial) | C40.2 | C79.51 | – | D16.2 | D48.0 | D49.2 |
| metacarpus (any bone) | C40.1 | C79.51 | – | D16.1 | – | – |
| metatarsus (any bone) | C40.3 | C79.51 | – | D16.3 | – | – |
| nose, nasal › bone | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| nose, nasal › turbinate (mucosa) › bone | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| nucleus pulposus | C41.2 | C79.51 | – | D16.6 | D48.0 | D49.2 |
| occipital › bone | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| orbit › bone | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| parietal › bone | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| patella | C40.2 | C79.51 | – | – | – | – |
| pelvis, pelvic › bone | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| phalanges › foot | C40.3 | C79.51 | – | D16.3 | – | – |
| phalanges › hand | C40.1 | C79.51 | – | D16.1 | – | – |
| pubic bone | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| radius (any part) | C40.0 | C79.51 | – | D16.0 | – | – |
| rib | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| sacrococcyx, sacrococcygeal | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| sacrum, sacral (vertebra) | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| scapula (any part) | C40.0 | C79.51 | – | D16.0 | – | – |
| sella turcica › bone | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| semilunar cartilage (knee) | C40.2 | C79.51 | – | D16.2 | D48.0 | D49.2 |
| sinus (accessory) › bone (any) | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| skeleton, skeletal NEC | C41.9 | C79.51 | – | D16.9 | D48.0 | D49.2 |
| skull | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| sphenoid › bone | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| spine, spinal (column) | C41.2 | C79.51 | – | D16.6 | D48.0 | D49.2 |
| spine, spinal (column) › coccyx | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| spine, spinal (column) › lumbosacral | C41.2 | C79.51 | – | D16.6 | D48.0 | D49.2 |
| spine, spinal (column) › sacrum | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| sternum | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
| symphysis pubis | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| tarsus (any bone) | C40.3 | C79.51 | – | D16.3 | – | – |
| temporal › bone | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| tibia (any part) | C40.2 | C79.51 | – | D16.2 | – | – |
| turbinate (bone) | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| ulna (any part) | C40.0 | C79.51 | – | D16.0 | – | – |
| vertebra (column) | C41.2 | C79.51 | – | D16.6 | D48.0 | D49.2 |
| vertebra (column) › coccyx | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| vertebra (column) › sacrum | C41.4 | C79.51 | – | D16.8 | D48.0 | D49.2 |
| vomer | C41.0 | C79.51 | – | D16.4 | D48.0 | D49.2 |
| xiphoid process | C41.3 | C79.51 | – | D16.7 | D48.0 | D49.2 |
Patient EducationClinical
Bone Cancer
Cancer that starts in a bone is uncommon. Cancer that has spread to the bone from another part of the body is more common.
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Convert C79.51 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About C79.51Overview
What is the ICD-10 code for secondary malignant neoplasm of bone?
The ICD-10-CM code for secondary malignant neoplasm of bone is C79.51 (sometimes written as C7951). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is C79.51 (Secondary malignant neoplasm of bone and bone marrow) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report secondary malignant neoplasm of bone on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does C79.51 group to?
When secondary malignant neoplasm of bone is the principal diagnosis on an inpatient stay, it groups to MS-DRG 543, 544, 456, 457, 542, 458, with relative weights from 0.7404 to 7.6211 depending on complications. Higher weights mean higher Medicare reimbursement.
Is C79.51 a CC or MCC?
CMS lists C79.51 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 22 closely related codes in its exclusion list.
Can C79.51 be reported with C7B.03?
Not as a rule. The Excludes1 note at C79.5, which applies to C79.51, lists "secondary carcinoid tumors of bone (C7B.03)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What HCC is C79.51?
C79.51 (secondary malignant neoplasm of bone) maps to CMS-HCC Category 18 (Cancer Metastatic to Bone, Other and Unspecified Metastatic Cancer; Acute Leukemia Except Myeloid), commonly written as HCC 18, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 8 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. In the Part D prescription drug model it maps to RxHCC 17.
Does C79.51 risk-adjust for Medicare Advantage payment?
Yes. When documented and reported on a Medicare Advantage encounter, C79.51 adds a risk adjustment factor of about 2.341 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 1.110 to 2.537 depending on the payment segment). A more severe related category (HCC 17) supersedes it when both are reported. See the full factor table on the HCC 18 category page.