2026 ICD-10-CM Diagnosis Code C74.90Malignant neoplasm of unspecified part of unspecified adrenal gland

ICD-10-CM Codes›C00–D49›C73-C75›C74

ICD-10-CM C74.90
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C74.90 is a billable ICD-10-CM diagnosis code for malignant neoplasm of unspecified part of unspecified adrenal gland. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 643 through 645. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Endocrine system cancers - all other types.

Code Identity

ICD-10-CM Code
C74.90
Billable Status
Yes — Valid for Submission
Code Describes
Malignant neoplasm of unspecified part of unspecified adrenal gland
Short Description
Malignant neoplasm of unsp part of unspecified adrenal gland
Parent Code
C74.9
Malignant neoplasm of unspecified part of adrenal gland

Code Classification

ChapterC00–D49Neoplasms
SectionC73-C75Malignant neoplasms of thyroid and other endocrine glands
CategoryC74Malignant neoplasm of adrenal gland
This CodeC74.90Malignant neoplasm of unspecified part of unspecified adrenal gland

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Abdominothoracic neuroblastoma
  • Adrenal neuroblastoma
  • International neuroblastoma pathology classification finding
  • International neuroblastoma pathology classification: Favorable histology group, patient age 1.5 years up to but less than 5 years, with differentiating neuroblastoma , and low mitosis-karyorrhexis index
  • International neuroblastoma pathology classification: Favorable histology group, patient less than 1.5 years of age, with poorly differentiated neuroblastoma , and low or intermediate mitosis-karyorrhexis index
  • International neuroblastoma pathology classification: Favorable histology group, patient of any age with ganglioneuroblastoma, intermixed
  • International neuroblastoma pathology classification: Favorable histology group, patient of any age with ganglioneuroma maturing, or mature
  • International neuroblastoma pathology classification: Unfavorable histology group, patient 1.5 yr up to but less than 5 yr, with poorly differentiated neuroblastoma and any MKI or differentiating neuroblastoma and intermediate or high MKI
  • International neuroblastoma pathology classification: Unfavorable histology group, patient 5 years or older, with any subtype of neuroblastoma and any mitosis-karyorrhexis index
  • International neuroblastoma pathology classification: Unfavorable histology group, patient less than 1.5 years old, with poorly differentiated or differentiating neuroblastoma and high mitosis-karyorrhexis index
  • International neuroblastoma pathology classification: Unfavorable histology group, patient of any age, with ganglioneuroblastoma, nodular
  • International neuroblastoma pathology classification: Unfavorable histology group, patient of any age, with undifferentiated neuroblastoma and any mitosis-karyorrhexis index
  • International neuroblastoma staging system stage 1
  • International neuroblastoma staging system stage 2A
  • International neuroblastoma staging system stage 2B
  • International neuroblastoma staging system stage 3
  • International neuroblastoma staging system stage 4
  • International neuroblastoma staging system stage 4S
  • International neuroblastoma staging system stage finding
  • Malignant neoplasm of adrenal gland
  • Metastatic malignant neoplasm to adrenal gland
  • Metastatic neuroblastoma
  • Metastatic neuroblastoma to abdominothoracic structure
  • Metastatic neuroblastoma to adrenal gland
  • Metastatic neuroblastoma to brain
  • Metastatic neuroblastoma to central nervous system
  • Metastatic neuroblastoma to paraspinal area
  • Metastatic neuroblastoma to pelvis
  • Metastatic neuroblastoma to thorax
  • Neuroblastoma
  • Neuroblastoma of brain
  • Neuroblastoma of central nervous system
  • Pelvic neuroblastoma
  • Primary adrenal neuroblastoma
  • Primary hyperaldosteronism due to aldosterone-secreting malignant neoplasm of adrenal gland
  • Primary malignant neoplasm of adrenal gland
  • Primary neuroblastoma
  • Thoracic neuroblastoma

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Neuroblastoma
      • unspecified site
    • Sympathicoblastoma
      • unspecified site

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO056
Endocrine system cancers - all other types
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Esthesioneuroblastoma, Olfactory

    a malignant olfactory neuroblastoma arising from the olfactory epithelium of the superior nasal cavity and cribriform plate. it is uncommon (3% of nasal tumors) and rarely is associated with the production of excess hormones (e.g., siadh, cushing syndrome). it has a high propensity for multiple local recurrences and bony metastases. (from holland et al., cancer medicine, 3rd ed, p1245; j laryngol otol 1998 jul;112(7):628-33)

  • Neuroblastoma

    a common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. this tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (from devita et al., cancer: principles and practice of oncology, 5th ed, pp2099-2101; curr opin oncol 1998 jan;10(1):43-51)

  • Retinoblastoma

    a malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. the tumor tends to occur in early childhood or infancy and may be present at birth. the majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. an abnormal pupil reflex (leukokoria); nystagmus, pathologic; strabismus; and visual loss represent common clinical characteristics of this condition. (from devita et al., cancer: principles and practice of oncology, 5th ed, p2104)

  • Metastatic Neuroblastoma

    a neuroblastoma that has metastasized from its original site of growth to another anatomic site.

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary		Malig.
Secondary		Ca
in situ		BenignUncertainUnspec.
adrenalC74.9C79.7D09.3D35.0D44.1D49.7
adrenal › capsuleC74.9C79.7D09.3D35.0D44.1D49.7
adrenal › glandC74.9C79.7D09.3D35.0D44.1D49.7
suprarenalC74.9C79.7D09.3D35.0D44.1D49.7
suprarenal › capsuleC74.9C79.7D09.3D35.0D44.1D49.7
suprarenal › glandC74.9C79.7D09.3D35.0D44.1D49.7

Patient EducationClinical

Adrenal Gland Cancer

Your adrenal, or suprarenal, glands are located on the top of each kidney. These glands produce hormones that you can't live without, including sex hormones and cortisol, which helps you respond to stress and has many other functions.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert C74.90 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
194.0 Malign neopl adrenal
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C74.90Overview

Is C74.90 (Malignant neoplasm of unspecified part of adrenal gland) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of unspecified part of unspecified adrenal gland on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C74.90 group to?

When malignant neoplasm of unspecified part of unspecified adrenal gland is the principal diagnosis on an inpatient stay, it groups to MS-DRG 643, 644, 645, with relative weights from 0.7683 to 1.6461 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of C74.90?

Under the General Equivalence Mappings, malignant neoplasm of unspecified part of unspecified adrenal gland converts to ICD-9-CM 194.0 (malign neopl adrenal). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.