2026 ICD-10-CM Diagnosis Code C54.0Malignant neoplasm of isthmus uteri
ICD-10-CM Codes›C00–D49›C51-C58›C54
- Billable — Valid for Submission
- Chronic Condition
C54.0 is a billable ICD-10-CM diagnosis code for malignant neoplasm of isthmus uteri. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 736 through 741, 754 through 756. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Female reproductive system cancers - uterus.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Complex mixed and stromal malignant neoplasm of isthmus uteri
- Malignant neoplasm of isthmus of uterine body
- Neoplasm of isthmus of uterus
- Primary malignant neoplasm of isthmus of uterus
- Primary rhabdomyosarcoma of abdomen
- Primary rhabdomyosarcoma of pelvis
- Rhabdomyosarcoma of corpus uteri
- Rhabdomyosarcoma of isthmus uteri
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Malignant neoplasm of lower uterine segment
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- Sarcoma (of) - See Also: Neoplasm, connective tissue, malignant;
- endometrial (stromal) - C54.1
- isthmus - C54.0
- stromal (endometrial) - C54.1
- isthmus - C54.0
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Sarcoma(of)
- endometrial (stromal)
- isthmus
- Sarcoma(of)
- stromal (endometrial)
- isthmus
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Table of NeoplasmsClinical
Anatomical sites in the Table of Neoplasms that reference this code family.
Patient EducationClinical
Uterine Cancer
Uterine cancer is a cancer that forms in tissues of the uterus, which is sometimes called the womb. The uterus is the place where a fetus grows during pregnancy.
The full article covers:
- What is uterine cancer?
- Who is more likely to develop uterine cancer?
- What are the symptoms of uterine cancer?
- How is uterine cancer diagnosed?
- What are the treatments for uterine cancer?
- Can uterine cancer be prevented?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert C54.0 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About C54.0Overview
Is C54.0 (Malignant neoplasm of corpus uteri) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of isthmus uteri on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does C54.0 group to?
When malignant neoplasm of isthmus uteri is the principal diagnosis on an inpatient stay, it groups to MS-DRG 736, 737, 738, 739, 740, 741, 754, 755, 756, with relative weights from 0.9605 to 3.5745 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of C54.0?
Under the General Equivalence Mappings, malignant neoplasm of isthmus uteri converts to ICD-9-CM 182.1 (mal neo uterine isthmus). The mapping is a direct match.
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.
