2026 ICD-10-CM Diagnosis Code C53.0Malignant neoplasm of endocervix

ICD-10-CM Codes›C00–D49›C51-C58›C53

ICD-10-CM C53.0
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C53.0 is a billable ICD-10-CM diagnosis code for malignant neoplasm of endocervix. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 736 through 741, 754 through 756. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Female reproductive system cancers - cervix.

Code Identity

ICD-10-CM Code
C53.0
Billable Status
Yes — Valid for Submission
Code Describes
Malignant neoplasm of endocervix
Short Description
Malignant neoplasm of endocervix
Same as the full description in the CMS dataset.
Parent Code
C53
Malignant neoplasm of cervix uteri

Code Classification

ChapterC00–D49Neoplasms
SectionC51-C58Malignant neoplasms of female genital organs
CategoryC53Malignant neoplasm of cervix uteri
This CodeC53.0Malignant neoplasm of endocervix

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Adenocarcinoma of cervix
  • Carcinoma of cervix
  • Carcinoma of endocervix
  • Endocervical adenocarcinoma
  • Malignant neoplasm of endocervical canal
  • Malignant neoplasm of endocervical gland
  • Malignant neoplasm of endocervix
  • Primary adenocarcinoma of cervix uteri
  • Primary adenocarcinoma of endocervix
  • Primary carcinoma of cervix
  • Primary carcinoma of endocervix
  • Primary malignant neoplasm of endocervix

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO032
Female reproductive system cancers - cervix
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary		Malig.
Secondary		Ca
in situ		BenignUncertainUnspec.
cervix (cervical) (uteri) (uterus) › canalC53.0C79.82D06.0D26.0D39.0D49.59
cervix (cervical) (uteri) (uterus) › endocervix (canal) (gland)C53.0C79.82D06.0D26.0D39.0D49.59
cervix (cervical) (uteri) (uterus) › internal osC53.0C79.82D06.0D26.0D39.0D49.59
cervix (cervical) (uteri) (uterus) › nabothian glandC53.0C79.82D06.0D26.0D39.0D49.59
endocervix (canal) (gland)C53.0C79.82D06.0D26.0D39.0D49.59
follicle, nabothianC53.0C79.82D06.0D26.0D39.0D49.59
internal › os (cervix)C53.0C79.82D06.0D26.0D39.0D49.59
nabothian gland (follicle)C53.0C79.82D06.0D26.0D39.0D49.59
os › internalC53.0C79.82D06.0D26.0D39.0D49.59
uterus, uteri, uterine › endocervix (canal) (gland)C53.0C79.82D06.0D26.0D39.0D49.59
uterus, uteri, uterine › internal osC53.0C79.82D06.0D26.0D39.0D49.59

Patient EducationClinical

Cervical Cancer

Cervical cancer is cancer that starts in the cells of the cervix. The cervix is part of the female reproductive system. It is the lower, narrow end of the uterus (womb), which opens into the vagina (birth canal).

The full article covers:

  • What is cervical cancer?
  • What causes cervical cancer?
  • Who is more likely to develop cervical cancer?
  • What are the symptoms of cervical cancer?
  • How is cervical cancer diagnosed?
  • What are the treatments for cervical cancer?
  • Can cervical cancer be prevented?
  • What is Cervical Cancer?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert C53.0 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
180.0 Malig neo endocervix
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C53.0Overview

Is C53.0 (Malignant neoplasm of cervix uteri) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of endocervix on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C53.0 group to?

When malignant neoplasm of endocervix is the principal diagnosis on an inpatient stay, it groups to MS-DRG 736, 737, 738, 739, 740, 741, 754, 755, 756, with relative weights from 0.9605 to 3.5745 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of C53.0?

Under the General Equivalence Mappings, malignant neoplasm of endocervix converts to ICD-9-CM 180.0 (malig neo endocervix). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.