2026 ICD-10-CM Diagnosis Code B48.4Penicillosis

ICD-10-CM Codes›A00–B99›B35-B49›B48

ICD-10-CM B48.4
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

B48.4 is a billable ICD-10-CM diagnosis code for penicillosis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 867 through 869. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Fungal infections.

Code Identity

ICD-10-CM Code
B48.4
Billable Status
Yes — Valid for Submission
Code Describes
Penicillosis
Short Description
Penicillosis
Same as the full description in the CMS dataset.
Parent Code
B48
Other mycoses, not elsewhere classified

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionB35-B49Mycoses
CategoryB48Other mycoses, not elsewhere classified
This CodeB48.4Penicillosis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Disseminated infection caused by Talaromyces marneffei
  • Infection caused by Penicillium
  • Infection caused by Penicillium bacillosporum
  • Infection caused by Penicillium bertai
  • Infection caused by Penicillium chrysogenum
  • Infection caused by Penicillium citreoviride
  • Infection caused by Penicillium citrinum
  • Infection caused by Penicillium commune
  • Infection caused by Penicillium crustaceum
  • Infection caused by Penicillium cyclopium
  • Infection caused by Penicillium expansum
  • Infection caused by Penicillium frequentans
  • Infection caused by Penicillium glaucum
  • Infection caused by Penicillium griseofulvum
  • Infection caused by Penicillium islandicum
  • Infection caused by Penicillium mycetomagenum
  • Infection caused by Penicillium oxalicum
  • Infection caused by Penicillium palitans
  • Infection caused by Penicillium puberulum
  • Infection caused by Penicillium purpurogenum
  • Infection caused by Penicillium roqueforte
  • Infection caused by Penicillium rugulosum
  • Infection caused by Penicillium spinulosum
  • Infection caused by Penicillium suberi
  • Infection caused by Penicillium verrucosum
  • Infection caused by Penicillium verruculosum
  • Infection caused by Penicillium viridicatum
  • Infection caused by Talaromyces marneffei
  • Penicillosis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Talaromycosis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Infection, infected, infective(opportunistic)
      • Penicillium (marneffei)
    • Penicillosis
    • Talaromycosis

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INF004
Fungal infections
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Fungal Infections

If you have ever had athlete's foot or a yeast infection, you can blame a fungus. A fungus is a primitive organism. Mushrooms, mold and mildew are examples. Fungi live in air, in soil, on plants and in water. Some live in the human body. Only about half of all types of fungi are harmful.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert B48.4 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
117.3 Aspergillosis
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About B48.4Overview

Is B48.4 (Other mycoses, not elsewhere classified) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report penicillosis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does B48.4 group to?

When penicillosis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 867, 868, 869, with relative weights from 0.7297 to 2.0932 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of B48.4?

Under the General Equivalence Mappings, penicillosis converts to ICD-9-CM 117.3 (aspergillosis). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.