2026 ICD-10-CM Diagnosis Code B00.52Herpesviral keratitis

ICD-10-CM Codes›A00–B99›B00-B09›B00

ICD-10-CM B00.52
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

B00.52 is a billable ICD-10-CM diagnosis code for herpesviral keratitis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 124 through 125, 974 through 976. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Cornea and external disease and Viral infection.

Code Identity

ICD-10-CM Code
B00.52
Billable Status
Yes — Valid for Submission
Code Describes
Herpesviral keratitis
Short Description
Herpesviral keratitis
Same as the full description in the CMS dataset.
Parent Code
B00.5
Herpesviral ocular disease

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionB00-B09Viral infections characterized by skin and mucous membrane lesions
CategoryB00Herpesviral [herpes simplex] infections
This CodeB00.52Herpesviral keratitis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Bilateral deposit in corneas
  • Bilateral disciform keratitis of eyes caused by Human herpes simplex virus
  • Bilateral interstitial keratitis caused by herpes simplex virus
  • Bilateral interstitial keratitis of eyes
  • Corneal endotheliitis
  • Dendritic keratitis of bilateral eyes caused by herpes simplex virus
  • Dendritic keratitis of left eye caused by herpes simplex virus
  • Dendritic keratitis of right eye caused by herpes simplex virus
  • Dendritic ulcer
  • Disciform keratitis
  • Disciform keratitis of left eye caused by herpes simplex virus
  • Disciform keratitis of right eye caused by herpes simplex virus
  • Herpes simplex conjunctivitis
  • Herpes simplex corneal endotheliitis
  • Herpes simplex dendritic keratitis
  • Herpes simplex disciform keratitis
  • Herpes simplex keratitis
  • Herpes simplex keratoconjunctivitis
  • Herpes simplex necrotizing stromal keratitis
  • Herpes simplex stromal keratitis
  • Herpes simplex subepithelial infiltrates
  • Herpes simplex virus epithelial keratitis
  • Infectious epithelial keratitis
  • Interstitial keratitis of left eye caused by herpes simplex virus
  • Interstitial keratitis of right eye caused by herpes simplex virus
  • Keratitis of bilateral eyes caused by herpes simplex virus
  • Keratitis of left eye caused by herpes simplex virus
  • Keratitis of right eye caused by herpes simplex virus
  • Necrotizing keratitis
  • Primary herpes simplex
  • Primary herpes simplex keratoconjunctivitis
  • Recurrent herpes simplex infection of cornea
  • Recurrent herpes simplex infection of eye
  • Recurrent herpetic keratitis
  • Viral corneal ulcer

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Herpesviral keratoconjunctivitis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Herpes, herpesvirus, herpetic
      • keratitis (simplex) (dendritic) (disciform) (interstitial)
    • Herpes, herpesvirus, herpetic
      • keratoconjunctivitis (simplex)
    • Herpes, herpesvirus, herpetic
      • simplex
        • keratitis (interstitial)
    • Keratitis(nodular) (nonulcerative) (simple) (zonular)
      • arborescens (herpes simplex)
    • Keratitis(nodular) (nonulcerative) (simple) (zonular)
      • dendritic (a) (herpes simplex)
    • Keratitis(nodular) (nonulcerative) (simple) (zonular)
      • disciform (is) (herpes simplex)
    • Keratitis(nodular) (nonulcerative) (simple) (zonular)
      • herpes, herpetic (simplex)
    • Keratitis(nodular) (nonulcerative) (simple) (zonular)
      • in (due to)
        • herpes (simplex) virus
    • Keratitis(nodular) (nonulcerative) (simple) (zonular)
      • interstitial (nonsyphilitic)
        • herpes, herpetic (simplex)
    • Keratoconjunctivitis
      • herpes, herpetic (simplex)
    • Ulcer, ulcerated, ulcerating, ulceration, ulcerative
      • cornea
        • dendritic (herpes simplex)
    • Ulcer, ulcerated, ulcerating, ulceration, ulcerative
      • dendritic, cornea (herpes simplex)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EYE001
Cornea and external disease
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR INF008
Viral infection
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Herpes Simplex

Herpes is an infection that is caused by a herpes simplex virus (HSV). Oral herpes causes cold sores around the mouth or face. Genital herpes affects the genitals, buttocks or anal area. Genital herpes is a sexually transmitted infection (STI). It affects the genitals, buttocks or anal area.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert B00.52 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
054.42 Dendritic keratitis
Approximate The match is approximate rather than exact.
ICD-9-CM
054.43 H simplex keratitis
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About B00.52Overview

Is B00.52 (Herpesviral ocular disease) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report herpesviral keratitis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does B00.52 group to?

When herpesviral keratitis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 124, 125, 974, 975, 976, with relative weights from 0.7678 to 2.8860 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of B00.52?

Under the General Equivalence Mappings, herpesviral keratitis converts to ICD-9-CM 054.42 (dendritic keratitis) and 054.43 (h simplex keratitis). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.